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Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing

bioRxiv

Aug 14, 2014

Konstantin BerlinAdam M. Phillippy

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Abstract

We report reference-grade de novo assemblies of four model organisms and the human genome from single-molecule, real-time (SMRT) sequencing. Long-read SMRT sequencing is routinely used to finish microbial genomes, but the available assembly methods have not scaled well to larger genomes...read more

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Small Molecule
Genome, Microbial
NCOR2 wt Allele
NCOR2 gene
Drosophila melanogaster
Genome Sequencing
Saccharomyces cerevisiae allergenic extract
Genome
Arabidopsis thaliana <plant>
HAL-2 protein, C elegans
133
1
12
Paper Details
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  • Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing

    bioRxiv

    Aug 14, 2014

    Konstantin BerlinAdam M. Phillippy

    PMID: 990008003

    DOI: 10.1101/008003

    Abstract

    We report reference-grade de novo assemblies of four model organisms and the human genome from single-molecule, real-time (SMRT) sequencing. Long-read SMRT sequencing is routinely used to finish microbial genomes, but the available assembly methods have not scaled well to larger genomes...read more

    Mentioned in this Paper

    Small Molecule
    Genome, Microbial
    NCOR2 wt Allele
    NCOR2 gene
    Drosophila melanogaster
    133
    1
    12
    Paper Details
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