Assessing autonomic function by analysis of heart rate recovery from exercise in healthy subjects

The American Journal of Cardiology
G L Pierpont, Eric J Voth

Abstract

Although delayed recovery of heart rate (HR) after exercise indicates poor prognosis, the relative role of parasympathetic reactivation versus sympathetic withdrawal in controlling exercise HR recovery remains controversial. Quantifying HR recovery is difficult because the rate of recovery varies with exercise level. This study develops a model of HR recovery applicable to multiple exercise levels simultaneously. Using the Levenberg-Marquardt method for nonlinear models, HR curves for 11 healthy volunteers recovering from 4 different levels of exercise were fit to equations incorporating 1 first-order time constant for parasympathetic reactivation and 1 for sympathetic withdrawal. Results provided time constants for parasympathetic reactivation of 44 +/- 37 seconds and for sympathetic withdrawal of 65 +/- 56 seconds. The model fit the HR recovery curves very closely, explaining 99.7 +/- 0.1% of the variance in the data. In conclusion, this study presents a unique method for quantitatively testing theories on the relative roles of sympathetic withdrawal and parasympathetic reactivation during recovery from exercise. It provides indexes of dynamic sympathetic and parasympathetic functions, with the parasympathetic system having a...Continue Reading

References

Jan 1, 1989·European Journal of Applied Physiology and Occupational Physiology·R PeriniA Veicsteinas
Apr 1, 1970·Cardiovascular Research·A D Jose, D Collison
Oct 28, 1999·The New England Journal of Medicine·C R ColeM S Lauer
Apr 28, 2000·Journal of the Autonomic Nervous System·G L PierpontC C Gornick

❮ Previous
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Citations

Oct 15, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Abdoulaye BaYves Jammes
Jun 30, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ergun Baris KayaAli Oto
Aug 10, 2007·European Journal of Applied Physiology·Jill Borresen, Michael I Lambert
Oct 19, 2007·European Journal of Applied Physiology·Kaisu Martinmäki, Heikki Rusko
Dec 1, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Kevin S HeffernanBo Fernhall
Jun 15, 2013·Pulmonary Medicine·Roberta P RamosJ Alberto Neder
Mar 4, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Esra Pancar YukselAhmet Yasar Turanli
Apr 29, 2014·Complementary Therapies in Clinical Practice·Fuitze TanSalim Fredericks
Mar 24, 2015·Journal of Science and Medicine in Sport·Rebecca L ThomsonJonathan D Buckley
Apr 1, 2011·Journal of Science and Medicine in Sport·Alessandro ArduiniMarco Romagnoli
Oct 26, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Stephen L WasmundSheldon E Litwin
Nov 17, 2009·International Journal of Cardiology·Ross ArenaMarco Guazzi
Sep 28, 2015·The Annals of Thoracic Surgery·Duc HaPeter J Mazzone
Aug 3, 2011·Psychophysiology·Jennifer L GordonSimon L Bacon
Mar 28, 2013·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Gordon L PierpontDemetri Yannopoulos
Jan 1, 2010·Clinical Cardiology·Marco GuazziRoss Arena
Jul 2, 2010·The Journal of Clinical Hypertension·Sercan OkutucuAli Oto
May 11, 2010·The American Journal of Cardiology·Goncalo V Mendonca, Fernando D Pereira
Apr 3, 2012·The American Journal of Cardiology·Nils P Johnson, Jeffrey J Goldberger
Apr 29, 2006·American Heart Journal·Joel W HughesRichard Josephson
Jun 2, 2007·American Heart Journal·Jonathan MyersPaul Dubach
Jan 18, 2011·Research in Developmental Disabilities·Goncalo V MendoncaBo Fernhall
Feb 6, 2009·International Journal of Cardiology·Marco GuazziRoss Arena
Dec 6, 2014·The Journal of Pediatrics·Anthony M AlvaradoRobert I Liem
Apr 30, 2016·Physiology & Behavior·J Álvarez-HermsM Burtscher
May 12, 2016·The Journal of Headache and Pain·Oleg V MamontovAlexei A Kamshilin
Dec 29, 2016·The Journal of Physiological Sciences : JPS·Anran WangDingchang Zheng
Jan 29, 2014·European Journal of Preventive Cardiology·Carlos Vieira DuarteClaudio Gil Soares de Araújo
Jan 22, 2013·European Journal of Preventive Cardiology·Lawrence P CahalinMarco Guazzi
Sep 7, 2018·The Annals of Otology, Rhinology, and Laryngology·Adrianna C ShembelKatherine Verdolini Abbott
Jul 24, 2013·Circulation·Gerald F FletcherUNKNOWN American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee of the Council on Clinical Cardiology,
Sep 17, 2014·Journal of Strength and Conditioning Research·Marco RomagnoliAlessandro Arduini
Aug 23, 2006·American Journal of Physical Medicine & Rehabilitation·Shyi-Kuen WuSen-Wei Tsai
Dec 6, 2008·Journal of Physiological Anthropology·Shigehiro SuzukiMichitaka Matsubara

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