Assessing blood vessel perfusion and vital signs through retinal imaging photoplethysmography

Biomedical Optics Express
Harnani HassanSijung Hu

Abstract

One solution to the global challenge of increasing ocular disease is a cost-effective technique for rapid screening and assessment. Current ophthalmic imaging techniques, e.g. scanning and ocular blood flow systems, are expensive, complex to operate and utilize invasive contrast agents during assessment. The work presented here demonstrates a simple retinal imaging photoplethysmography (iPPG) system with the potential to provide screening, diagnosis, monitoring and assessment that is non-invasive, painless and radiationless. Time series of individual retinal blood vessel images, captured with an eye fundus camera, are processed using standard filtering, amplitude demodulation and principle component analysis (PCA) methods to determine the values of the heart rate (HR) and respiration rate (RR), which are in compliance with simultaneously obtained measurements using commercial pulse oximetry. It also seems possible that some information on the dynamic changes in oxygen saturation levels (SpO2) in a retinal blood vessel may also be obtained. As a consequence, the retinal iPPG modality system demonstrates a potential avenue for rapid ophthalmic screening, and even early diagnosis, against ocular disease without the need for fluore...Continue Reading

References

Apr 30, 2008·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Alon HarrisBrent Siesky
Sep 29, 2011·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Rui BernardesConceição Lobo
Jun 16, 2012·Investigative Ophthalmology & Visual Science·William H MorganDao-Yi Yu
Nov 1, 2012·Journal of Biomedical Optics·Yu SunStephen Greenwald
Nov 30, 2013·Journal of Healthcare Engineering·Sijung HuJia Zheng
Sep 4, 2014·Investigative Ophthalmology & Visual Science·William H MorganPhilip H House
Oct 7, 2014·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Neeru Gupta, Ivo Kocur
Oct 29, 2015·Maturitas·Madeleine Zetterberg
Jul 16, 2016·Progress in Retinal and Eye Research·William H MorganDao-Yi Yu
Dec 27, 2016·Biomedical Optics Express·Mark van GastelGerard de Haan

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Citations

Sep 23, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ralf-Peter TornowFolkert Horn
Jul 2, 2021·Computer Methods and Programs in Biomedicine·Maciej Czepita, Anna Fabijańska

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