PMID: 11918621Mar 29, 2002Paper

Assessing diabetic control--reliability of methods available in resource poor settings

Diabetic Medicine : a Journal of the British Diabetic Association
A P RotchfordG V Gill

Abstract

To examine the reliability of random venous or capillary blood glucose testing, random urine glucose testing, and a current symptom history in predicting a high HbA1c in Type 2 diabetic patients taking oral hypoglycaemic agents in a poorly controlled rural African population. For a cut-off point for HbA1c of > or = 8%, for random venous plasma glucose of > or = 14 mmol/L (present in 47.2% of subjects), specificity was 97.1% (95% CI 85.1-99.9), sensitivity 56.8% (48.8-64.5) and positive predictive value (PPV) 98.9% (94.2-99.9). HbA1c > or = 8% is predicted by a random capillary blood glucose of 17 mmol/L (present in 28.4% of subjects) with specificity 100% (90.0-100.0), PPV 100% (93.7-100.0) and sensitivity of 34.3% (27.2-42.1). HbA1c > or = 8% is predicted by the presence of heavy glycosuria (> or = 55 mmol/L) (present in 35.6%) with specificity 94.1% (80.3-99.3), sensitivity of 41.9% (34.1-49.9) and PPV 97.1% (89.9-99.6). Polyuria/nocturia (present in 31.3%) was the only symptom found to be associated with poor control, with a specificity for predicting HbA1c of > or = 8% of 81.5% (61.9-93.7), PPV 89.1% (76.4-96.4) and sensitivity 30.6% (22.9-39.1). Where resources are short, random glucose testing can be used to detect a sign...Continue Reading

References

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Citations

Feb 14, 2006·BJU International·Luba W GourovaPhilip E V A van Kerrebroeck
Sep 10, 2014·The Lancet. Diabetes & Endocrinology·Anca Lelia RizaReinout van Crevel
Apr 20, 2006·Diabetes Research and Clinical Practice·M AbdelgadirC Berne
Jul 21, 2017·Pediatric Diabetes·Frida SundbergRagnar Hanas
May 1, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·G V GillD Wilkinson
May 1, 2004·Tropical Doctor·Atakilt GebrekidanSolomon Tesfaye

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