Abstract
Haemophilia is a group of inherited, congenital diseases present all through the life. Those disorders are associated with a chronic burden of morbidity punctuated by episodes of acute deterioration in health-related quality-of-life (HR-QL). The significances of assessing HR-QL in individuals with haemophilia as an important component of the clinical database have gained increasing recognition in recent years. To the best of our knowledge, reports on the HR-QL of Chinese patients with haemophilia are not available. The purpose of this paper was to assess the HR-QL of patients with haemophilia in China. In order to do this, 179 patients with haemophilia (age 16-70) were mailed China quality-of-life questionnaire, which was designed specially for this study taking into account the culture characters of Chinese. Compared with the normal male general population, individuals with haemophilia experienced significantly lower levels of HR-QL and within the subgroups of patients, there was a gradation of HR-QL from mild < moderate < severe haemophilia patients. Age, clinical severity, degree of arthropathy, hepatitis status, salary and mean annual expenditure for replacement therapy were predictors of HR-QL. Clinical severity of the dis...Continue Reading
References
Jan 28, 1989·BMJ : British Medical Journal·C SmitE Briët
Jun 1, 1985·American Journal of Epidemiology·R E JohnsonC J Carman
Jan 1, 1983·Acta Medica Scandinavica·S A Larsson, B Wiechel
Sep 1, 1982·British Journal of Haematology·E IkkalaV Rasi
Oct 1, 1994·Journal of Internal Medicine·L M AledortH Pettersson
Jul 1, 1994·Transfusion Medicine Reviews·V BlanchetteM Inwood
Feb 1, 1994·American Journal of Hematology·T L ChorbaB L Evatt
Jan 30, 1993·BMJ : British Medical Journal
Nov 1, 1995·Social Science & Medicine
Oct 1, 1996·Critical Care Medicine·R Brooks
Dec 3, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·A H MinersC A Lee
Jan 3, 2001·Haemophilia : the Official Journal of the World Federation of Hemophilia·S Solovieva
Apr 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·D R GlobeG Kominski
Nov 1, 2002·American Journal of Hematology·Ronald D BarrIrwin Walker
Citations
May 29, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·T M BrownC L Pashos
May 29, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·D GlobeUNKNOWN Healthrelated Quality Of Life Expert Working Group Of The International Prophylaxis Study Group
Feb 16, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·L ScaloneUNKNOWN COCIS Study Investigators
Jul 22, 2008·Haemophilia : the Official Journal of the World Federation of Hemophilia·M-C Poon, K-H Luke
Apr 4, 2008·Haemophilia : the Official Journal of the World Federation of Hemophilia·H K HartlI Pabinger
Jul 13, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·S AzharN Muhammad
Jul 13, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·Margareth C OzeloRenchi Yang
Nov 21, 2013·Haemophilia : the Official Journal of the World Federation of Hemophilia·J WindygaJ H Ramirez
Feb 17, 2015·Haemophilia : the Official Journal of the World Federation of Hemophilia·C M ChenS L Hsu
Jun 6, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Monika BullingerSylvia von Mackensen
Sep 8, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·J SunUNKNOWN Chinese HERO study group
Dec 9, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·T SalomonS V Peixoto
Nov 21, 2016·Archives of Physical Medicine and Rehabilitation·Rubén Cuesta-BarriusoJosé Antonio López-Pina
Jul 21, 2017·Pediatric Hematology and Oncology·Yongqiang ZhaoJing Sun
Apr 18, 2019·Haemophilia : the Official Journal of the World Federation of Hemophilia·Renchi YangNikki Church
Nov 18, 2017·Haemophilia : the Official Journal of the World Federation of Hemophilia·Z LiJ Xiao
Feb 9, 2018·Medicine·Wei-Min ChuYu-Tse Tsan