Assessing patient preferences in heart failure using conjoint methodology

Patient Preference and Adherence
Giovanni PisaStephan Hupfer

Abstract

The course of heart failure (HF) is characterized by frequent hospitalizations, a high mortality rate, as well as a severely impaired health-related quality of life (HRQoL). To optimize disease management, understanding of patient preferences is crucial. We aimed to assess patient preferences using conjoint methodology and HRQoL in patients with HF. Two modules were applied: an initial qualitative module, consisting of in-depth interviews with 12 HF patients, and the main quantitative module in 300 HF patients from across Germany. Patients were stratified according to the time of their last HF hospitalization. Each patient was presented with ten different scenarios during the conjoint exercise. Additionally, patients completed the generic HRQoL instrument, EuroQol health questionnaire (EQ-5D™). The attribute with the highest relative importance was dyspnea (44%), followed by physical capacity (18%). Of similar importance were exhaustion during mental activities (13%), fear due to HF (13%), and autonomy (12%). The most affected HRQoL dimensions according to the EQ-5D questionnaire were anxiety/depression (23% with severe problems), pain/discomfort (19%), and usual activities (15%). Overall average EQ-5D score was 0.39 with stabl...Continue Reading

Citations

May 16, 2017·Journal of Clinical Epidemiology·Paco M WelsingUNKNOWN Work Package 3 of the GetReal Consortium
Nov 6, 2018·PharmacoEconomics·Vikas SoekhaiCaroline M Vass
Jan 20, 2019·Western Journal of Nursing Research·Seongkum HeoStephanie Turrise
Jul 14, 2017·Current Medical Research and Opinion·A Brett HauberChun-Lan Chang
Dec 1, 2020·PharmacoEconomics·Gian Luca Di TannaGary Globe
Mar 12, 2021·PloS One·Colleen A McHorneyGary Globe

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