Abstract
The objective of this study was to demonstrate the use of the Heckman two-step method to assess and correct for bias due to missing health related quality of life (HRQL) surveys in a clinical study of acute coronary syndrome (ACS) patients. We analyzed data from 2,733 veterans with a confirmed diagnosis of acute coronary syndromes (ACS), including either acute myocardial infarction or unstable angina. HRQL outcomes were assessed by the Short-Form 36 (SF-36) health status survey which was mailed to all patients who were alive 7 months following ACS discharge. We created multivariable models of 7-month post-ACS physical and mental health status using data only from the 1,660 survey respondents. Then, using the Heckman method, we modeled survey non-response and incorporated this into our initial models to assess and correct for potential bias. We used logistic and ordinary least squares regression to estimate the multivariable selection models. We found that our model of 7-month mental health status was biased due to survey non-response, while the model for physical health status was not. A history of alcohol or substance abuse was no longer significantly associated with mental health status after controlling for bias due to non-r...Continue Reading
Citations
Sep 26, 2013·Current Opinion in Pulmonary Medicine·Ariel Tarasiuk, Haim Reuveni
Apr 3, 2012·Health and Quality of Life Outcomes·Andrew HutchingsJan van der Meulen
Feb 6, 2014·PloS One·Maarten van VlietPeter Pickkers
Dec 19, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Ezra GabbayDana C Miskulin
Oct 29, 2013·Oncology Nursing Forum·Janet HardenLaurel Northouse
Apr 16, 2014·AIDS Care·Taoufiq DouabUNKNOWN ANRS-VESPA2 Study Group
Oct 19, 2017·European Heart Journal. Quality of Care & Clinical Outcomes·Salla OinasmaaAnna-Maija Tolppanen
Oct 10, 2018·Statistics in Medicine·Manuel GomesGiampiero Marra
Dec 29, 2007·Medical Care·Meredith L KilgoreStephen E Brossette
Jun 28, 2005·Breast Cancer Research and Treatment·Andrea A ThorntonJohn P Pierce
Aug 30, 2014·Health and Quality of Life Outcomes·Kristofer Bandayrel, Bradley C Johnston
Jun 14, 2019·Circulation. Cardiovascular Quality and Outcomes·Jacob V SpertusJohn A Spertus
Aug 20, 2011·Psychiatry and Clinical Neurosciences·Haekyung Jeon-SlaughterBarbara Neas
Feb 15, 2020·Statistics in Medicine·Manuel GomesJames Carpenter
Feb 20, 2016·Statistics in Medicine·Jacques-Emmanuel GalimardMatthieu Resche-Rigon
Sep 17, 2016·PloS One·Helder Novais BastosMargarida Saraiva
Apr 8, 2014·Liver International : Official Journal of the International Association for the Study of the Liver·Linda S YangDavid L Morris
Jun 28, 2014·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Mohamed A ImamRichard E Field
Feb 1, 2018·European Heart Journal. Quality of Care & Clinical Outcomes·Krishnaraj S Rathod, Andrew Wragg
Dec 16, 2010·Expert Review of Pharmacoeconomics & Outcomes Research·Farzan SiddiquiBenjamin Movsas