Assessing short-term effects and costs at an early stage of innovation: the use of positron emission tomography on radiotherapy treatment decision making

International Journal of Technology Assessment in Health Care
R RemonnayMarie-Odile Carrère

Abstract

Positron emission tomography (PET) is an innovative imaging tool. Associated with computed tomography (CT), it allows a better definition for the tumor volume for radiotherapy, compared with CT only. The aim of this study was to assess the effects of PET on resource allocation (costs and savings) and on the choice of the following treatment in radiotherapy. In 2004 and 2005, 209 patients were enrolled (97 patients with Hodgkin's disease and 112 with non-small cell lung cancer) in a national study conducted in eight hospitals. Two treatment decisions made on the basis of CT only or CT associated with PET, were compared in a prospective study where each subject was his/her own control. The direct medical cost of using PET was assessed by microcosting, using data collected from specific questionnaires. The costs of new tests and the costs and savings associated with changes in the chosen treatment were calculated on the basis of reimbursement rates. The mean cost of using PET was approximately euro 800 per patient (50 percent for the radionuclide 18F-FDG [2-[18F]fluoro-2-deoxy-D-glucose]). Radiotherapy treatments were modified for 10 percent of patients with Hodgkin's disease versus 40 percent of patients with lung cancer. Overall...Continue Reading

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Citations

Sep 7, 2012·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·P PommierJ-L Lagrange
Jan 1, 2012·PET Clinics·Juliano Julio CerciStefano Fanti
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Nov 26, 2008·International Journal of Radiation Oncology, Biology, Physics·Michael Mac Manus, Rodney J Hicks
Feb 10, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Juliano J CerciJosé C Meneghetti
Apr 29, 2016·Japanese Journal of Radiology·Kazuhiro KitajimaKozo Kuribayashi

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