Assessing the Content Validity of a New Patient-Reported Measure of Barriers to Antiretroviral Therapy Adherence for Electronic Administration in Routine HIV Care: Proposal for a Web-Based Delphi Study

JMIR Research Protocols
Kim EnglerBertrand Lebouché

Abstract

Adherence to lifesaving antiretroviral therapy (ART) for HIV infection remains a challenge for many patients. Routine screening for barriers to ART adherence could help make HIV care more patient-centered and prevent virologic rebound or failure. Our team is currently developing a new HIV-specific patient-reported outcome measure (PROM) of these barriers for use in Canada and France along with a digital app for its electronic administration. In our previous work, we developed the PROM's multidimensional conceptual framework and generated 100 English items, which have been translated to French. This study aims to use a Web-based Delphi to help validate and select the content of this new HIV-specific PROM, based on the perspective of anglophone and francophone patients and providers in Canada and France. Here, we present the proposal for this Delphi. This modified Delphi will involve a diverse panel of patients (n=32) and providers (n=52) recruited especially from the 9 sites of the PROM development study (site locations in Canada: Montreal, Toronto, Vancouver; in France: Paris, Nantes, Clermont-Ferrand, Saint-Martin, Cayenne). Overall, 2 rounds of Web-based questionnaires will be conducted. The threshold for consensus is set at ...Continue Reading

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References

Jun 1, 1994·Journal of Advanced Nursing·H P McKenna
May 29, 2000·The Journal of the Association of Nurses in AIDS Care : JANAC·R L Sowell
Feb 13, 2003·Journal of Advanced Nursing·Catherine Powell
Apr 5, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Diane WildUNKNOWN ISPOR Task Force for Translation and Cultural Adaptation
Jul 27, 2007·Research in Nursing & Health·Denise F PolitSteven V Owen
Mar 21, 2008·Journal of Advanced Nursing·Satu Elo, Helvi Kyngäs
Apr 7, 2011·AIDS and Behavior·Carmen OrtegoJavier Vejo
Apr 20, 2011·Patient Education and Counseling·L Alison PhillipsHoward Leventhal
Nov 2, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael S KozakJames H Willig
Feb 1, 2012·AIDS and Behavior·M Barton LawsIra B Wilson
Jan 5, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Bryce B ReeveZeeshan Butt
Dec 10, 2013·The American Journal of Hospice & Palliative Care·Katie E Mosack, Rachael L Wandrey
Dec 10, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maria-Jose Santana, David Feeny
Jan 1, 2013·Health Services Insights·Theresa Weldring, Sheree M S Smith
May 13, 2015·Journal of Clinical Epidemiology·Kurt KroenkeJacob Kean
Aug 26, 2015·AIDS Care·Rob J FredericksenDonald L Patrick
Feb 1, 2012·Journal of AIDS and HIV Research·R FredericksenH M Crane
Jan 16, 2016·Journal of the American Board of Family Medicine : JABFM·Bethany M KwanLisa M Schilling
Aug 4, 2016·Systematic Reviews·David O FrancisIrene D Feurer
Sep 18, 2016·The Patient·Kim EnglerBertrand Lebouché
Oct 14, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Isabelle ToupinBertrand Lebouché
Dec 7, 2017·JMIR Research Protocols·Mallory O JohnsonKaterina A Christopoulos
Mar 20, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·C B TerweeL B Mokkink
May 3, 2018·Journal of Medical Internet Research·Conceição GranjaMonika Alise Johansen
Sep 5, 2018·AIDS Patient Care and STDs·Valerie YelvertonNathan Thielman

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