Assessing the determinants of stillbirths and early neonatal deaths using routinely collected data in an inner city area

BMC Medicine
Nigel C SmeetonCharles Wolfe

Abstract

Within the UK there is considerable variation in the perinatal mortality rate. The objective of this study was to assess the factors associated with stillbirths and early neonatal deaths (ENND) and the suitability of the available databases in a health authority with one of the highest rates in the country. Two case-control studies were carried out in three hospital trusts in the Lambeth, Southwark and Lewisham Health Authority, London, using routinely collected information. In one study, 342 stillbirths and 1,368 controls were included, and in the other study, 205 ENND and 820 controls were included. In the two studies cases and controls were matched for hospital trust. A birthweight below 1.5 kg was found in 54% and 48% of the stillbirths and ENND, respectively. More than 50% of the cases, stillbirths and ENND, had a length of gestation below 32 weeks. Length of gestation, birthweight, emergency caesarean section and age of the mother were associated with stillbirths. Birthweight and Apgar score at 1 minute as a categorical variable were associated with ENND. There was no direct evidence of an effect of social deprivation on the outcomes of interest. Birthweight and length of gestation are the most influential factors on an u...Continue Reading

References

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Citations

Jun 16, 2012·BMJ Open·Alison L WeightmanFrank D Dunstan
Jan 16, 2008·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Ling HuangCarl van Walraven
May 20, 2014·Acta Obstetricia Et Gynecologica Scandinavica·Amber A VosSemiha Denktaş
Feb 3, 2018·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Folashade Olufunke OmokhodionIgor Burstyn
Dec 20, 2017·Journal of Perinatal Medicine·Joanna YuSailesh Kumar
Mar 26, 2008·Fetal and Pediatric Pathology·Michael B BrimacombeStacy Zamudio

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