Assessing the predictive value of teacher reports in a high risk sample for schizophrenia: a ROC analysis

Schizophrenia Research
S S OlinS A Mednick

Abstract

We examined teachers' reports to determine early patterns of school behavior that identify children who were diagnosed schizophrenic in adulthood. High risk subjects (n = 207) in the Copenhagen High Risk for schizophrenia project were examined on a 25-item questionnaire completed by teachers. A likelihood ratio approach was used to create a classification index relating school report to DSM-IIIR diagnoses made 31 years later. A standard receiver operating characteristic (ROC) analysis was used to evaluate the efficacy of the classification indices for distinguishing preschizophrenics from children who later developed schizotypal disorder, other nonpsychotic disorders, and no mental illness. Different items predicted schizophrenia in males and females. To a significantly greater degree than their controls, preschizophrenic males were lonely and rejected, behaved inappropriately, were disciplinary problems, emotionally high strung, and were more likely to have repeated a grade; preschizophrenic females were nervous and passive. Both preschizophrenic males and females were judged by teachers to be vulnerable to future psychotic problems. These findings are consistent with our preliminary findings, as well as with other research. T...Continue Reading

References

Oct 1, 1992·The British Journal of Psychiatry : the Journal of Mental Science·S Lewis
Jul 1, 1972·The Journal of Nervous and Mental Disease·N F Watt

❮ Previous
Next ❯

Citations

Sep 8, 2010·European Child & Adolescent Psychiatry·David GyllenbergFredrik Almqvist
Dec 17, 2003·Psychiatry Research·Yong-Guan Ang, Hao-Yang Tan
Feb 20, 2003·Schizophrenia Research·Laura T NiemiJouko K Lönnqvist
Aug 12, 2005·Journal of Child and Adolescent Psychopharmacology·William S StoneUNKNOWN Consortium on the Genetics on Schizophrenia
Jul 17, 1999·Acta Psychiatrica Scandinavica·J W CarterS A Mednick
Mar 12, 2004·Annual Review of Psychology·R M McFall, T A Treat
May 31, 2001·Acta Psychiatrica Scandinavica·T K LarsenP Vaglum
Oct 22, 2005·The British Journal of Clinical Psychology·Oliver J Mason, Julie Beavan-Pearson
Apr 5, 2012·Pharmacoepidemiology and Drug Safety·David GyllenbergFredrik Almqvist
Mar 15, 2006·European Psychiatry : the Journal of the Association of European Psychiatrists·Virva SiiraKristian Làksy
Jul 2, 2008·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Elisa Kijner GuttFrancisco Lotufo-Neto
Jun 24, 2008·Nordic Journal of Psychiatry·Raimo K R Salokangas, Thomas H McGlashan
Sep 10, 2013·Aggressive Behavior·Zoe StephensonClaire Cooke
Mar 10, 2016·Harvard Review of Psychiatry·Mohajer Abbass Hameed, Andrew James Lewis
Jun 14, 2016·Scandinavian Journal of Child and Adolescent Psychiatry and Psychology·Angela M Reiersen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.