Assessing the quality of proton PBS treatment delivery using machine log files: comprehensive analysis of clinical treatments delivered at PSI Gantry 2

Physics in Medicine and Biology
D ScandurraAntony J Lomax

Abstract

Pencil beam scanning (PBS) proton therapy requires the delivery of many thousand proton beams, each modulated for position, energy and monitor units, to provide a highly conformal patient treatment. The quality of the treatment is dependent on the delivery accuracy of each beam and at each fraction. In this work we describe the use of treatment log files, which are a record of the machine parameters for a given field delivery on a given fraction, to investigate the integrity of treatment delivery compared to the nominal planned dose. The dosimetry-relevant log file parameters are used to reconstruct the 3D dose distribution on the patient anatomy, using a TPS-independent dose calculation system. The analysis was performed for patients treated at Paul Scherrer Institute on Gantry 2, both for individual fields and per series (or plan), and delivery quality was assessed by determining the percentage of voxels in the log file dose distribution within  +/-  1% of the nominal dose. It was seen that, for all series delivered, the mean pass rate is 96.4%. Furthermore, this work establishes a correlation between the delivery quality of a field and the beam position accuracy. This correlation is evident for all delivered fields regardles...Continue Reading

References

Mar 11, 1999·Physics in Medicine and Biology·A Lomax
Feb 9, 2011·International Journal of Radiation Oncology, Biology, Physics·X Ronald ZhuNarayan Sahoo

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Citations

Oct 20, 2018·Medical Physics·Danairis Hernandez MoralesJoshua B Stoker
Dec 13, 2018·Physics in Medicine and Biology·Carla WinterhalterSairos Safai
Jul 17, 2018·Physics in Medicine and Biology·C WinterhalterS Safai
Jun 6, 2017·Physics in Medicine and Biology·G KlimpkiD Meer
Jun 24, 2020·Physics in Medicine and Biology·Michael MatterFrancesca Albertini
Jul 18, 2019·Physics in Medicine and Biology·C BulaD Meer
Feb 7, 2017·Physics in Medicine and Biology·O ActisA Mayor
Dec 21, 2016·Physics in Medicine and Biology·Yuting LinKyung-Wook Jee
Feb 7, 2018·Physics in Medicine and Biology·Miriam KriegerYe Zhang
Oct 11, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Dominic MaesJatinder Saini

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