Assessing the relationship between compliance with antidepressant therapy and employer costs among employees in the United States

Journal of Occupational and Environmental Medicine
Howard G BirnbaumPaul Greenberg

Abstract

To assess effects of antidepressant treatment compliance on health care and workplace costs. By using workplace survey data linked to two employers' health care claims, employees with depression/antidepressant claims were categorized into noncompliant/compliant groups. Annualized costs were compared between compliance groups, for the employees with antidepressant use and a subset diagnosed with depression. Among antidepressant users (N = 1224), medical costs were not statistically different for compliant versus noncompliant patients; drug costs were higher for compliant patients, primarily because of antidepressants' costs. Similar associations were observed among depressed patients (N = 488). Absenteeism costs were lower for compliant patients with antidepressant use ($3857 vs $4,907, P = 0.041) and among depressed patients ($3976 vs $5899, P = 0.047). Presenteeism costs were higher for depressed compliant patients ($19,170 vs $15,829, P = 0.011). Increased compliance with antidepressants is significantly associated with reduced absenteeism costs.

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Citations

Jan 1, 2012·The Primary Care Companion to CNS Disorders·Haijun TianEdward Kim
Sep 14, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Raymond W LamChinnapalli V Manjunath
Jan 11, 2016·Journal of Affective Disorders·Siew Ching HoSabrina Anne Jacob
Apr 30, 2016·Journal of Child and Adolescent Psychopharmacology·Alessandro S De NadaiEric A Storch
Sep 12, 2014·Psychodynamic Psychiatry·William H Sledge, Susan G Lazar
Jan 12, 2019·Psychiatric Services : a Journal of the American Psychiatric Association·Fraser W GasparCarolyn S Dewa
Jun 10, 2011·Journal of Occupational and Environmental Medicine·Ronald LoeppkeDoris Konicki
Oct 13, 2017·Journal of Affective Disorders·Ignacio Aznar-LouMaria Rubio-Valera

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