Assessing the Relative Biological Effectiveness of Neutrons across Organs of Varying Depth among the Atomic Bomb Survivors

Radiation Research
Kismet A Cordova, Harry M Cullings

Abstract

When assessing radiation-related risk among the atomic bomb survivors, choices in modeling approach can have an important impact on the results, which are then used to inform radiation protection standards throughout the world. The atomic bombings of Hiroshima and Nagasaki produced a mixed-field radiation exposure from two sources: neutrons and gamma rays. Neutrons are more densely ionizing and cause greater biological damage per unit absorbed dose, resulting in greater relative biological effectiveness (RBE) than gamma rays. To account for this, a combined weighted dose is typically calculated as the sum of the gamma-ray dose and 10 times the neutron dose in the Radiation Effects Research Foundation's reports of mortality, solid cancer incidence and other outcomes. In addition, the colon, which is often chosen as the whole-body representative organ in these analyses, is relatively deep in the body and therefore its dose calculation involves heavy body shielding of neutrons and a low neutron/gamma-ray ratio. With added follow-up and recently updated doses, we used a data-driven approach to determine the best-fitting neutron RBE for a range of organs of varying depth. Aggregated person-year tables of solid cancer incidence (1958...Continue Reading

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Citations

Feb 23, 2021·Life Sciences in Space Research·Luana HafnerUwe Schneider
May 1, 2021·Radiation and Environmental Biophysics·Linda WalshUwe Schneider
Feb 16, 2021·Radiation Research·Daniela L StricklinLanyn P Taliaferro
Sep 23, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Luana Hafner, Linda Walsh

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