Assessing the stimulant effects of alcohol in humans

Pharmacology, Biochemistry, and Behavior
Dena DavidsonR M Swift

Abstract

The stimulant effects of alcohol were assessed in humans. Twenty social drinkers were tested in dyads in the laboratory on three separate occasions, held 7 days apart. For their first session, one-third of the group consumed a dose of alcohol that was calculated to reach a target peak blood alcohol concentration (BAC) of 0.05 g/dl, one-third of the group consumed placebo-alcohol, and one-third consumed diet Sprite. For alcohol and placebo-alcohol conditions, subjects were told that they may or may not be given alcohol. For the soda condition, subjects were told they were consuming soda. Subjective stimulation, activity levels, and speech production were assessed over a 15-min period after beverage consumption (posttreatment) and compared to measurements taken prior to beverage consumption (baseline). Scores on the stimulant subscale of the Biphasic Alcohol Effects Scale (BAES) were significantly greater for the alcohol condition relative to the soda condition. There was also a trend for stimulant scores to be greater for the alcohol condition relative to the placebo-alcohol condition. Activity levels were significantly greater for the alcohol condition compared to either the placebo-alcohol or soda conditions. There were no gro...Continue Reading

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Citations

Dec 18, 2007·Psychopharmacology·William R CorbinKim Fromme
Feb 13, 2010·Addiction Biology·John C CrabbeCindy L Ehlers
Mar 19, 2014·Pharmacology, Biochemistry, and Behavior·Christian BrabantEtienne Quertemont
May 27, 2014·Psychopharmacology·Christopher W KahlerDamaris J Rohsenow
Mar 27, 2009·Alcoholism, Clinical and Experimental Research·Sandra Y RuegerAndrea C King
Feb 14, 2007·Alcoholism, Clinical and Experimental Research·Caroline Brunelle, Robert O Pihl
Apr 4, 2015·Alcoholism, Clinical and Experimental Research·Carolina L Haass-KofflerRobert M Swift
Jun 1, 2006·Pharmacology, Biochemistry, and Behavior·Gregory Blakley, Larissa A Pohorecky
Jul 9, 2004·Annals of the New York Academy of Sciences·Patricia Patterson-BuckendahlRichard Kvetnansky
Nov 16, 2006·Annals of the New York Academy of Sciences·Sergio AbanadesRafael De La Torre
Feb 12, 2008·Alcoholism, Clinical and Experimental Research·Henry R KranzlerCheryl Oncken
Oct 24, 2007·Alcoholism, Clinical and Experimental Research·Merideth A AddicottDonald M Dougherty
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Nov 16, 2007·Journal of Clinical Psychopharmacology·Sergio AbanadesRafael de la Torre
Nov 2, 2019·Neuroscience and Biobehavioral Reviews·Roberto U CofresíThomas M Piasecki

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