Assessing the value of screening tools: reviewing the challenges and opportunities of cost-effectiveness analysis

Public Health Reviews
Nicolas Iragorri, Eldon Spackman

Abstract

Screening is an important part of preventive medicine. Ideally, screening tools identify patients early enough to provide treatment and avoid or reduce symptoms and other consequences, improving health outcomes of the population at a reasonable cost. Cost-effectiveness analyses combine the expected benefits and costs of interventions and can be used to assess the value of screening tools. This review seeks to evaluate the latest cost-effectiveness analyses on screening tools to identify the current challenges encountered and potential methods to overcome them. A systematic literature search of EMBASE and MEDLINE identified cost-effectiveness analyses of screening tools published in 2017. Data extracted included the population, disease, screening tools, comparators, perspective, time horizon, discounting, and outcomes. Challenges and methodological suggestions were narratively synthesized. Four key categories were identified: screening pathways, pre-symptomatic disease, treatment outcomes, and non-health benefits. Not all studies included treatment outcomes; 15 studies (22%) did not include treatment following diagnosis. Quality-adjusted life years were used by 35 (51.4%) as the main outcome. Studies that undertook a societal pe...Continue Reading

References

Sep 8, 2000·PharmacoEconomics·A Brennan, R Akehurst
Jan 22, 2003·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Milton C WeinsteinUNKNOWN ISPOR Task Force on Good Research Practices--Modeling Studies
Jun 18, 2005·Journal of Health Economics·Anirban Basu, David Meltzer
Sep 5, 2008·PharmacoEconomics·Christopher McCabeAnthony J Culyer
Oct 1, 2008·BMJ : British Medical Journal·Michael DrummondBrian Ferguson
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
Sep 2, 2011·Transfusion·Barbara A Borkent-RavenBen A van Hout
Apr 24, 2014·JAMA Internal Medicine·Anna N A TostesonEtta D Pisano
May 24, 2014·Journal of Occupational and Environmental Medicine·Johanna M van DongenJudith E Bosmans
Jan 28, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·C L van VelzenM C Haak
Mar 14, 2016·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Fredrik Salvesen HaukaasEline Aas
May 10, 2016·Arthritis Care & Research·Wietske KievitCalin D Popa
Aug 28, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Nowlan SelvapattAshley Brown
Oct 16, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M YoshimuraT Takiguchi
Oct 19, 2016·Journal of the National Cancer Institute·Jane J KimNicole G Campos
Oct 21, 2016·Applied Health Economics and Health Policy·Andrew KellerTroy Gianduzzo
Nov 20, 2016·International Journal of Cancer. Journal International Du Cancer·P A van LuijtH J de Koning
Dec 8, 2016·Obstetrics and Gynecology·Catherine M AlbrightErika F Werner
Jan 6, 2017·Bulletin of the World Health Organization·G Suzanne A SmitBrecht Devleesschauwer
Jan 13, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L Lapointe-ShawA McGeer
Jan 14, 2017·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Wiebren A A TjalmaKatleen Vandeweyer
Jan 17, 2017·Journal of the American Academy of Dermatology·Lara FerrándizDavid Moreno-Ramírez
Jan 25, 2017·Cancer·Afsaneh BarziSarmad Sadeghi
Feb 9, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Benjamin CadierUNKNOWN ANRS CO12 CirVir and CHANGH groups
Feb 25, 2017·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·K K K HtetS Thein
Mar 4, 2017·Journal of the American Heart Association·Kathryn RobertsJonathan R Carapetis
Mar 16, 2017·BMC Nephrology·Benjamin O YarnoffUNKNOWN Centers for Disease Control and Prevention CKD Initiative
Mar 28, 2017·The Journal of Arthroplasty·Devin M WilliamsHassan M K Ghomrawi
Apr 1, 2017·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Karl Ulrich PetryAnja Neumann

❮ Previous
Next ❯

Citations

Feb 2, 2021·Journal of the Neurological Sciences·Eavan McGovernEmmanuel Roze
Apr 14, 2021·Sexually Transmitted Infections·Yannick Hoyos-MallecotUNKNOWN DRASEXP collaborative group
Aug 28, 2021·International Journal of Environmental Research and Public Health·Jose Manuel MontesCristina Jenaro
Aug 28, 2021·Journal of Personalized Medicine·Bartha M KnoppersNora Pashayan
Sep 28, 2021·Journal of Psychosomatic Obstetrics and Gynaecology·Flavia de Lima OsórioSusan Ayers

❮ Previous
Next ❯

Methods Mentioned

BETA
total hip arthroplasty
genotyping
X-ray

Software Mentioned

Flex sig
Emtree

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.