Assessing the value of Western Cape Provincial Government health administrative data and electronic pharmacy records in ascertaining medicine use during pregnancy

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
U MehtaAndrew Boulle

Abstract

In African settings, where there is a high disease burden, there is a need to improve the science of documenting and analysing accurate information regarding medicine exposures in women immediately before and during pregnancy to assess the extent of use and safety in pregnant women and their unborn children. To compare evidence of medicine use during pregnancy, as documented in paper-based clinical records (maternity case records (MCRs)) against electronic health information resources (Provincial Health Data Centre (PHDC)) and assess the level of concordance between the two as part of baseline investigations before piloting a provincial pregnancy exposure registry and birth defect surveillance system. The PHDC consolidates electronic clinical and pharmacy data. A folder review of completed pregnancies between November 2013 and January 2016 was conducted on randomly selected MCRs from midwife-run obstetric units and a secondary maternity hospital in Cape Town, South Africa. Medication exposures in the MCR were captured and compared with a customised PHDC data extract. The type and timing of drug exposures were compared. Total exposures were compiled from all data sources. Two hundred and six MCRs from three facilities were sampl...Continue Reading

Citations

Dec 14, 2018·Systematic Reviews·Bey-Marrié SchmidtNatalie Leon
Aug 28, 2020·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Ushma MehtaMarc Blockman

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pharmacotherapy

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