Assessment and follow-up of alcohol-dependent liver transplantation patients. A clinical cohort

General Hospital Psychiatry
R A TringaliM A Dew

Abstract

We describe pretransplantation characteristics of 103 consecutive alcoholic cirrhotics who underwent orthotopic liver transplantation over a 28-month period, and follow-up characteristics for 58 of 82 survivors. We examined whether certain pretransplantation psychiatric and demographic variables predicted posttransplantation outcomes. Patients who were sober < or = 6 months and those who died after transplantation had longer transplant hospital stays, suggesting that physiological compromise may predict posttransplant course. Using survival analyses because of variable follow-up intervals, only age over 50 years and index hospital stays greater than 1 month showed statistical trends toward predicting shorter posttransplant survival duration. Neither pretransplant sobriety, gender, nor duration of pretransplant heavy drinking predicted posttransplant survival duration. No variable, including preoperative sobriety < or = 6 months or attendance at alcohol rehabilitation peritransplant, predicted relapse except for female gender and pretransplant unemployment, in which cases the relapse rate was doubled. Our relapse rate of 21% is comparable to recidivism rates reported from other centers and for the general alcoholic population. T...Continue Reading

References

Oct 1, 1992·Alcoholism, Clinical and Experimental Research·T P BeresfordM R Lucey
Jan 1, 1991·Transplantation·R D GordonT E Starzl
Jan 1, 1990·Psychosomatics·T P BeresfordM Lucey
Dec 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A ParésJ Rodés
Feb 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S KumarT E Starzl
Feb 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S SchenkerM F Sorrell
Jan 1, 1989·The International Journal of the Addictions·N J PiazzaR D Yeager
Sep 1, 1983·The Western Journal of Medicine·M A Schuckit
May 1, 1984·The American Journal of Medicine·P J Frawley
Jul 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R A Krom

❮ Previous
Next ❯

Citations

Jul 14, 1999·Psychosomatics·C L WoodmanJ N Kline
Mar 10, 2001·Clinics in Liver Disease·S J MunozC Manzarbeitia
Jan 11, 2014·World Journal of Gastroenterology : WJG·Paula IruzubietaEmilio Fábrega
Mar 27, 2002·The Psychiatric Clinics of North America·Andrea DiMartiniMarian Fireman
Mar 15, 2005·Clinics in Liver Disease·Rowen K Zetterman
Oct 14, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Pascal PerneyGeorges-Philippe Pageaux
Apr 28, 2006·Clinical Transplantation·Katharina FierzSabina De Geest
Sep 30, 2009·The Mount Sinai Journal of Medicine, New York·Hui-Hui TanPaul Martin
May 12, 2012·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Johann-Martin HempelManfred E Beutel
Dec 13, 2006·Zeitschrift für Psychosomatische Medizin und Psychotherapie·Yesim ErimWolfgang E Senf
Mar 13, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·D M BravataD K Owens
Mar 20, 2002·Addiction Biology·Georges-Philippe PageauxDominique Larrey
Jun 27, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·George GeorgiouEd Day
Sep 24, 2004·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Joseph K Lim, Emmet B Keeffe
Dec 18, 2007·The American Journal of Gastroenterology·David S KotlyarRobert M Weinrieb
Feb 1, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mary Amanda DewJoel Greenhouse
May 26, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Andrea DiMartiniJohn Fung
Oct 23, 2010·Transplantation·Gurprataap S SandhuAlexander S Goldfarb-Rumyantzev
Sep 27, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Lois E Krahn, Andrea DiMartini
Oct 27, 2015·World Journal of Gastroenterology : WJG·José Ursic-BedoyaGeorges-Philippe Pageaux
Mar 10, 2001·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·M A DewR L Kormos
Jul 12, 2008·Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]·Diogo Telles-CorreiaE Monteiro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Robert M WeinriebM R Lucey
Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
G EversonThomas P Beresford
© 2021 Meta ULC. All rights reserved