Assessment and management of the risk of SARS-CoV-2 infection in an IVF laboratory

Reproductive Biomedicine Online
Roberta MaggiulliLaura Rienzi

Abstract

The study set out to identify corrective measures aimed at reducing the risk of aerosol-mediated viral infection within an IVF laboratory. A failure modes and effect analysis (FMEA) was conducted by a multidisciplinary IVF team. A schematic representation of new protocols and procedures adopted during COVID-19 emergency has been defined, including directives about the behaviour to adopt when entering the clinic and the laboratory, in case of face-to-face contact with patients and between staff members. In addition, the risk of cross-contamination between samples belonging to different patients during cell handling and manipulation has been evaluated. Potential failure modes for each phase of the emergency have been analysed, focusing on possible sources of error. Risk priority numbers have been calculated as products of Occurrence × Severity × Detection scores. Except for cell-cell contamination, which was considered highly unlikely, failure modes during patient-staff, staff-staff and staff-cell interactions were estimated as carrrying a moderate to high risk of infection. The main corrective measures entailed precautionary logistic measures, the implementation of additional personal protective equipment and changes in the IVF ...Continue Reading

Citations

Feb 6, 2021·Journal of Assisted Reproduction and Genetics·Catello ScaricaLucia De Santis
Feb 26, 2021·Journal of Human Reproductive Sciences·Padma Rekha JirgeDeepak Modi
Jun 2, 2021·Systems Biology in Reproductive Medicine·George AnifandisIoannis E Messinis
Jul 3, 2021·International Journal of Environmental Research and Public Health·Laihao MaKai Wei
Nov 24, 2020·Urologia Internationalis·Peng JinJayoung Kim

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