Assessment and treatment of bipolar disorder in the elderly

Drugs & Aging
J H EasthamR C Young

Abstract

The aetiology of late-onset bipolar disorder is heterogeneous because the disease is more likely to have a secondary (i.e. a medical disorder or medication-induced) cause in older than in younger patients. Elderly patients with bipolar disorder typically require lithium dosages that are 25 to 50% lower than those used in younger individuals. Information on the use of valproic acid (sodium valproate) in elderly patients with bipolar disorder is limited but encouraging. In contrast, there is virtually no information regarding the use of carbamazepine or other drugs in this patient group. Electroconvulsive therapy is well tolerated by older people and can be useful for these patients.

Citations

May 10, 2000·Drugs & Aging·B A SprouleK I Shulman
Jan 25, 2005·Drugs & Aging·Martha SajatovicNicoleta Coconcea
May 21, 2009·CNS Drugs·Etienne Marc Grandjean, Jean-Michel Aubry
May 4, 2011·The Psychiatric Clinics of North America·Martha Sajatovic, Peijun Chen
Feb 14, 2007·The American Journal of Geriatric Pharmacotherapy·Rehan AzizRajesh R Tampi
Sep 24, 2004·Bipolar Disorders·Colin A Depp, Dilip V Jeste
Jun 17, 2011·Bipolar Disorders·Gin S MalhiSamuel Gershon
Mar 18, 2004·Clinics in Geriatric Medicine·William J Burke, Steven P Wengel
Sep 14, 2000·International Journal of Geriatric Psychiatry·J Snowdon
Mar 7, 2012·The Australian and New Zealand Journal of Psychiatry·Gin S MalhiMichael Berk
Dec 15, 2004·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Ricardo Alberto MorenoRoberto Ratzke

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