Assessment in the Survival Outcome After Transarterial Chemoembolization Combined with Cryoablation for Hepatocellular Carcinoma (Diameter > 4cm) Based on the Albumin-Bilirubin Grade and Platelet-Albumin-Bilirubin ‎grade: ‎ A Preliminary Study

Cancer Management and Research
Zhimei HuangJinhua Huang

Abstract

Based on the albumin-bilirubin (ALBI) and platelet-albumin-bilirubin (PALBI) grade to assess the long-term outcomes of patients with large hepatocellular carcinoma (HCC) after transarterial chemoembolization combined with cryoablation (TACE-CRA). We studied 86 patients with HCC nodules (up to 3 HCCs with maximum diameters of 4.1-12.0 cm) who subsequently underwent TACE-CRA from July 2007 to August 2018. The overall survival (OS) was compared between groups classified by ALBI and PALBI grade. Baseline characteristics were collected to identify the risk factors for determination of poor OS after TACE-CRA. The prognostic performances of CTP class, ALBI and PALBI grade were compared. After a median follow-up time of 33.8 months, 41 patients had died. The cumulative1-, 3- and 5-year OS rates were 74.5%, 38.0% and 29.3%, respectively. Stratified according to ALBI grade, the cumulative 3- and 5-year OS rates were 41.2% and 41.2% in grade 1, respectively, and 20.9% and 9.8% in grades 2-3, respectively (P < 0.001). Stratified according to PALBI grade, the cumulative 3- and 5-year OS rates were 41.2% and 37.5% in grade 1, respectively, and 36.3% and 21.2% in grades 2-3, respectively (P = 0.002). Multivariate analysis results showed that ...Continue Reading

References

Sep 30, 2003·Journal of Vascular and Interventional Radiology : JVIR·David SacksCurtis A Lewis
Mar 5, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jordi BruixUNKNOWN American Association for the Study of Liver Diseases
Jan 13, 2012·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal
Feb 1, 2014·Lancet·Emmanuel A TsochatzisAndrew K Burroughs
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Oct 7, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Chunping WangYongping Yang
Jun 21, 2015·Journal of Vascular and Interventional Radiology : JVIR·Nishita KotharyDaniel Y Sze
Jul 25, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gin-Ho Lo
Sep 12, 2015·Journal of Clinical and Translational Hepatology·Li-Zhi NiuKe-Cheng Xu
Oct 13, 2015·World Journal of Gastroenterology : WJG·Koichiro Yamakado, Shozo Hirota
Mar 11, 2016·Abdominal Radiology·Peter J LittrupAnthony Shields
Jan 9, 2018·Lancet·Alejandro FornerJordi Bruix
May 4, 2018·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Hao HuBo Zhai
Sep 12, 2018·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Wei CuiJiaping Li
Aug 28, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Jia-Yan NiJin-Hua Huang

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