Assessment of a novel implantable artificial anal sphincter

Diseases of the Colon and Rectum
C A HajivassiliouI G Finlay

Abstract

The aim of the study was to test a new implantable artificial anal sphincter in the porcine model. The artificial sphincter, which includes an inflatable expander that compresses and flattens the bowel against a pillow, was implanted in 16 animals and studied for periods of up to 20 weeks. The anal sphincters were destroyed, and the efficacy of the device in rendering the animals continent was studied. Of the 11 animals in which the artificial sphincter was regularly closed, 8 completed the study and were continent during 85 percent of activation times. There was no evidence of ischemic injury. Major complications were related only to failure of the control pumps of the device. This study suggests that this neosphincter produces fecal continence without intestinal ischemia. At present reliability is limited only by the performance of the pump.

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Citations

Dec 25, 2003·Journal of Pediatric Surgery·Kotaro NishiRyoji Ohi
Jan 6, 1999·The British Journal of Surgery·C A Hajivassiliou, I G Finlay
Mar 1, 1999·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland· Hajivassiliou, Finlay
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Apr 22, 2011·Artificial Organs·Zong-Hai HuangXin-Jun Han
Sep 13, 2006·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Yun LuoHidetoshi Matsuki
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Jun 7, 2006·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy· Lirici Hüscher
Jul 24, 1998·Annals of Medicine·J Christiansen
Sep 24, 2004·The British Journal of Surgery·I G FinlayC A Hajivassiliou
Dec 23, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·K N Bitar, S Raghavan
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May 10, 2017·Diseases of the Colon and Rectum·Judith EversP Ronan O'Connell

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