Assessment of acute myocarditis by cardiac magnetic resonance imaging: Comparison of qualitative and quantitative analysis methods

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Massimo ImbriacoAlberto Cuocolo

Abstract

To compare cardiac magnetic resonance (CMR) qualitative and quantitative analysis methods for the noninvasive assessment of myocardial inflammation in patients with suspected acute myocarditis (AM). A total of 61 patients with suspected AM underwent coronary angiography and CMR. Qualitative analysis was performed applying Lake-Louise Criteria (LLC), followed by quantitative analysis based on the evaluation of edema ratio (ER) and global relative enhancement (RE). Diagnostic performance was assessed for each method by measuring the area under the curves (AUC) of the receiver operating characteristic analyses. The final diagnosis of AM was based on symptoms and signs suggestive of cardiac disease, evidence of myocardial injury as defined by electrocardiogram changes, elevated troponin I, exclusion of coronary artery disease by coronary angiography, and clinical and echocardiographic follow-up at 3 months after admission to the chest pain unit. In all patients, coronary angiography did not show significant coronary artery stenosis. Troponin I levels and creatine kinase were higher in patients with AM compared to those without (both P < .001). There were no significant differences among LLC, T2-weighted short inversion time inversi...Continue Reading

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Citations

Feb 13, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·G Ross Farris, Steven G Lloyd
Jul 19, 2019·Journal of Cardiovascular Medicine·Andrea PonsiglioneMassimo Imbriaco
Sep 7, 2019·Journal of Cardiovascular Translational Research·Maria Angela LosiEmanuele Barbato
May 16, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Wael A AlJaroudi, Fadi G Hage
Apr 17, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Shira Peleg HassonMichal Laufer-Perl
Jan 5, 2021·European Journal of Radiology Open·Andrea PonsiglioneAlberto Cuocolo

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