Assessment of anxiety in open field and elevated plus maze using infrared thermography

Physiology & Behavior
Benjamin LecorpsChristophe Féron

Abstract

Due to their direct inaccessibility, affective states are classically assessed by gathering concomitant physiological and behavioral measures. Although such a dual approach to assess emotional states is frequently used in different species including humans, the invasiveness of procedures for physiological recordings particularly in smaller-sized animals strongly restricts their application. We used infrared thermography, a non-invasive method, to assess physiological arousal during open field and elevated plus maze tests in mice. By measuring changes in surface temperature indicative of the animals' emotional response, we aimed to improve the inherently limited and still controversial information provided by behavioral parameters commonly used in these tests. Our results showed significant and consistent thermal responses during both tests, in accordance with classical physiological responses occurring in stressful situations. Besides, we found correlations between these thermal responses and the occurrence of anxiety-related behaviors. Furthermore, initial temperatures measured at the start of each procedure (open field, elevated plus maze), which can be interpreted as a measure of the animals' initial physiological arousal, p...Continue Reading

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Citations

Sep 4, 2019·Journal of Dairy Science·Thomas EdeDaniel M Weary
Nov 7, 2018·Scientific Reports·Benjamin LecorpsMarina A G von Keyserlingk
Jun 5, 2020·Animals : an Open Access Journal From MDPI·Sandra Martínez-ByerOxána Bánszegi
Jun 14, 2017·Reviews in the Neurosciences·Robert Lalonde, Catherine Strazielle
Jul 24, 2020·Animal Cognition·Aurélie VerjatChristophe Féron
Jun 12, 2020·Frontiers in Behavioral Neuroscience·Jamshid Faraji, Gerlinde A S Metz

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