Assessment of bagging GBLUP for whole-genome prediction of broiler chicken traits

Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie
R Abdollahi-ArpanahiD Gianola

Abstract

Bootstrap aggregation (bagging) is a resampling method known to produce more accurate predictions when predictors are unstable or when the number of markers is much larger than sample size, because of variance reduction capabilities. The purpose of this study was to compare genomic best linear unbiased prediction (GBLUP) with bootstrap aggregated sampling GBLUP (Bagged GBLUP, or BGBLUP) in terms of prediction accuracy. We used a 600 K Affymetrix platform with 1351 birds genotyped and phenotyped for three traits in broiler chickens; body weight, ultrasound measurement of breast muscle and hen house egg production. The predictive performance of GBLUP versus BGBLUP was evaluated in different scenarios consisting of including or excluding the TOP 20 markers from a standard genome-wide association study (GWAS) as fixed effects in the GBLUP model, and varying training sample sizes and allelic frequency bins. Predictive performance was assessed via five replications of a threefold cross-validation using the correlation between observed and predicted values, and prediction mean-squared error. GBLUP overfitted the training set data, and BGBLUP delivered a better predictive ability in testing sets. Treating the TOP 20 markers from the GW...Continue Reading

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Citations

Feb 5, 2016·Genetics, Selection, Evolution : GSE·Rostam Abdollahi-ArpanahiDaniel Gianola
Mar 14, 2016·Journal of Dairy Science·Ashley A MikshowskyKent A Weigel
Oct 19, 2016·Animal : an International Journal of Animal Bioscience·N Formoso-RaffertyJ P Gutiérrez
Jul 20, 2016·PloS One·Manman ShenNing Yang
Jan 18, 2017·Genetics, Selection, Evolution : GSE·Hossein MehrbanNoelia Ibáñez-Escriche

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Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie
R Abdollahi-ArpanahiD Gianola
Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie
R Abdollahi-ArpanahiD Gianola
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