Assessment of Cardiovascular Disease Risk and Therapeutic Patterns among Urban Black Rheumatoid Arthritis Patients.

Medical Sciences : Open Access Journal
Isabel M McFarlaneSrinivas Kolla

Abstract

Rheumatoid arthritis (RA) patients have nearly twice the risk of cardiovascular disease (CVD) compared to the general population. We aimed to assess, in a predominantly Black population, the prevalence of traditional and RA-specific CVD risk factors and therapeutic patterns. Utilizing ICD codes, we identified 503 RA patients ≥18 years old who were seen from 2010 to 2017. Of them, 88.5% were Black, 87.9% were women and 29.4% were smokers. CVD risk factors (obesity, diabetes, hypertension, dyslipidemia) were higher than in previously reported White RA cohorts. Eighty-seven percent of the patients had at least one traditional CVD risk factor, 37% had three or more traditional CVD risk factors and 58% had RA-specific risk factors (seropositive RA, >10 years of disease, joint erosions, elevated inflammatory markers, extra-articular disease, body mass index (BMI) < 20). CV outcomes (coronary artery disease/myocardial infarction, heart failure, atrial fibrillation and stroke) were comparable to published reports. Higher steroid use, which increases CVD risk, and lesser utilization of biologics (decrease CV risk) were also observed. Our Black RA cohort had higher rates of traditional CVD risk factors, in addition to chronic inflammatio...Continue Reading

References

Jul 16, 1999·Seminars in Arthritis and Rheumatism·C A Peschken, J M Esdaile
Mar 12, 2003·Circulation·Daniel H SolomonGary C Curhan
Mar 8, 2005·Arthritis and Rheumatism·Hilal Maradit-KremersSherine E Gabriel
Mar 3, 2007·Arthritis and Rheumatism·John M DavisSherine E Gabriel
Nov 28, 2008·Arthritis and Rheumatism·J Antonio Aviña-ZubietaDiane Lacaille
Dec 14, 2011·The New England Journal of Medicine·Iain B McInnes, Georg Schett
Mar 18, 2015·Arthritis & Rheumatology·D H SolomonJ D Greenberg
Jun 23, 2015·Arthritis Care & Research·Bryant R EnglandTed R Mikuls
Feb 13, 2018·Mediators of Inflammation·Arduino A MangoniGian Luca Erre
Mar 25, 2018·The Canadian Journal of Cardiology·Reto D Kurmann, Rekha Mankad
Apr 20, 2018·International Journal of Rheumatic Diseases·Maryam SanjadiSaeed Aslani

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Citations

Sep 1, 2019·Clinical Rheumatology·Isabel M McFarlaneStephen Anthony Waite

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Methods Mentioned

BETA
ESR

Software Mentioned

CORRONA
SPSS

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