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Assessment of doxorubicin delivery devices based on tailored bare polycaprolactone against glioblastoma

International Journal of Pharmaceutics

Mar 10, 2019

Enrique NizaAntonio Otero

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Abstract

Bare polycaprolactones with controlled molar mass and dispersity were employed to manufacture biodegradable devices, which were applied for doxorubicin delivery in glioblastoma. Micro- and nanoscale devices were prepared by emulsion formation or by a combination of precipitation and hyd...read more

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Mice, Inbred C57BL
Nanocrystalline Materials
oligo(caprolactone)
Polyesters
Scanning Electron Microscopy
C6 gene
Study
Macrophages, Peritoneal
Evaluation
Photon Correlation Spectroscopy
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Assessment of doxorubicin delivery devices based on tailored bare polycaprolactone against glioblastoma

International Journal of Pharmaceutics

Mar 10, 2019

Enrique NizaAntonio Otero

PMID: 30639216

DOI: 10.1016/j.ijpharm.2018.12.079

Abstract

Bare polycaprolactones with controlled molar mass and dispersity were employed to manufacture biodegradable devices, which were applied for doxorubicin delivery in glioblastoma. Micro- and nanoscale devices were prepared by emulsion formation or by a combination of precipitation and hyd...read more

Mentioned in this Paper

Mice, Inbred C57BL
Nanocrystalline Materials
oligo(caprolactone)
Polyesters
Scanning Electron Microscopy

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