Assessment of duodenogastric reflux by combined continuous intragastric pH and bilirubin monitoring

World Journal of Gastroenterology : WJG
Fei DaiXue-Qin Wang

Abstract

To assess the diagnostic value of a combination of continuous intragastric pH and bilirubin monitoring in the detection of duodenogastric reflux (DGR), and the effects of diet on the bilirubin absorbance. 30 healthy volunteers were divided into two groups: standard diet group (Group 1) 18 cases, free diet group (Group 2)12 cases. Each subjects were subjected to simultaneous 24-hour intragastric pH and spectrophotometric bilirubin concentration monitoring (Bilitec 2000). There was no difference of preprandial phase bilirubin absorbance between two groups. The absorbance of postprandial phase was significantly increased in group 2 than group 1. There was no difference between preprandial phase and postprandial phase absorbance in group 1. Postprandial phase absorbance was significantly higher in group 2. In a comparison of bile reflux with intragastric pH during night time, there were 4 types of reflux: Simultaneous increase in absorbance and pH in only 19.6%, increase in bilirubin with unchanged pH 33.3%, pH increase with unchanged absorbance 36.3%, and both unchanged in 10.8%. Linear regression analysis showed no correlation between percentage total time of pH<4 and percentage total time of absorbance>0.14, r=0.068 P<0.05. Beca...Continue Reading

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Citations

Jan 18, 2003·World Journal of Gastroenterology : WJG·Ying XinJian-Ming Si
Jan 11, 2005·World Journal of Gastroenterology : WJG·Pei-Song SongZe-Feng Chen
Apr 11, 2015·Gastroenterology Research and Practice·Alastair M SammonJehu E Iputo
Dec 13, 2017·Obesity Surgery·Thomas A EldredgeJonathan Shenfine
Nov 8, 2003·World Journal of Gastroenterology : WJG·Jin-Yan LuoJun Gong

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