Assessment of Eating Behavior Disturbance and Associated Neural Networks in Frontotemporal Dementia

JAMA Neurology
Rebekah M AhmedJohn R Hodges

Abstract

Abnormal eating behaviors are common in patients with frontotemporal dementia (FTD), yet their exact prevalence, severity, and underlying biological mechanisms are not understood. To define the severity of abnormal eating behavior and sucrose preference and their neural correlates in patients with behavioral variant FTD (bvFTD) and semantic dementia. Forty-nine patients with dementia (19 with bvFTD, 15 with semantic dementia, and 15 with Alzheimer disease) were recruited, and their eating behavior was compared with that of 25 healthy controls. The study was conducted from November 1, 2013, through May 31, 2015, and data analyzed from June 1 to August 31, 2015. Patients participated in an ad libitum breakfast test meal, and their total caloric intake and food preferences were measured. Changes in eating behavior were also measured using the Appetite and Eating Habits Questionnaire (APEHQ) and the Cambridge Behavioral Inventory (CBI). Sucrose preference was tested by measuring liking ratings of 3 desserts of varying sucrose content (A: 26%, B: 39%, C: 60%). Voxel-based morphometry analysis of whole-brain 3-T high-resolution brain magnetic resonance imaging was used to determine the gray matter density changes across groups and th...Continue Reading

Citations

Nov 1, 2016·Brain : a Journal of Neurology·Rebekah M AhmedJohn R Hodges
Mar 30, 2017·Journal of Geriatric Psychiatry and Neurology·Massimiliano BuoliAlfredo Carlo Altamura
Oct 21, 2016·American Journal of Alzheimer's Disease and Other Dementias·Gabriele CiprianiAngelo Nuti
Mar 24, 2018·Nature Reviews. Neurology·Rebekah M AhmedMatthew C Kiernan
Mar 21, 2018·Nature Neuroscience·Matthew A WhiteJemeen Sreedharan
Feb 7, 2018·Frontiers in Molecular Neuroscience·Pauline VercruysseLuc Dupuis
May 16, 2018·Brain : a Journal of Neurology·Stephanie WongFiona Kumfor
Jul 18, 2018·Annals of Neurology·Yu ChenOlivier Piguet
Jun 7, 2016·Journal of the International Neuropsychological Society : JINS·Mary R NewsomeHarvey S Levin
Aug 29, 2019·Annals of Clinical and Translational Neurology·Rebekah M AhmedOlivier Piguet
Oct 17, 2019·Journal of Neuropsychology·Miriam VignandoMarilena Aiello
Nov 28, 2018·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Gerardo SalvatoGabriella Bottini
May 31, 2019·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Shyuan T NgoFrederik J Steyn
May 1, 2018·Journal of Neurology, Neurosurgery, and Psychiatry·Frederik J SteynShyuan T Ngo
May 2, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Zhi ZhouXiaoyun Zheng
Aug 21, 2019·Neuropsychology Review·Yu ChenOlivier Piguet
Mar 6, 2018·Journal of Alzheimer's Disease : JAD·John R Hodges, Olivier Piguet
Apr 12, 2020·Journal of Neurology·Alexander G MurleyJames B Rowe
Jul 8, 2020·Alzheimer's Research & Therapy·Nathalie PhilippiUNKNOWN AlphaLewyMA study group
Aug 17, 2020·Acta Neuropathologica·Yuriko KatsumataPeter T Nelson
Dec 30, 2016·Brain : a Journal of Neurology·Elizabeth C Finger
Mar 27, 2019·Annals of Clinical and Translational Neurology·Rebekah M AhmedMatthew C Kiernan
Dec 15, 2020·Translational Neuroscience·Pan WangYuying Zhou
Feb 2, 2021·Neurobiology of Aging·Sara OberrauchLaura H Jacobson
Apr 7, 2021·Archives of Gerontology and Geriatrics·Ayami MeguroHirohiko Hirano
Apr 13, 2021·Brain : a Journal of Neurology·Siobhán R ShawMuireann Irish
May 12, 2021·Annals of Clinical and Translational Neurology·Rebekah M AhmedOlivier Piguet
Aug 7, 2021·Journal of Neurology, Neurosurgery, and Psychiatry·Marina CattaneoChristian Lunetta
Aug 25, 2021·CNS Drugs·Christine Le, Elizabeth Finger
Aug 31, 2021·Brain Communications·Martina BocchettaJonathan D Rohrer
Nov 14, 2018·Dementia and Geriatric Cognitive Disorders·Courtney LewisAdam P Vogel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Alzheimer's Disease: Neuroimaging

Neuroimaging can help identify pathological hallmarks of Alzheimer's disease (AD). Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.