PMID: 9436799Jan 22, 1998Paper

Assessment of endocrine functions in children following severe head trauma

Pediatric Neurology
M GoldmanJ Meyerovitch

Abstract

The goal of the present study was to assess endocrine functions in children following severe head trauma. Subjects included 21 children between the ages of 3 years and 18 years 6 months, referred to the Pediatric Rehabilitation Unit at Sheba Medical Center, Israel, between 1984 and 1995. Each was examined 4 months to 11 years following the first admission, undergoing a complete physical examination, including neurologic assessment, biochemical and baseline endocrine profiles, and bone age determination. A GnRH stimulation test was performed in prepubescent children who had advanced bone age. Sixteen children had experienced the head trauma before, or at onset of puberty, according to their chronologic ages. Two children had completed puberty before the head trauma. A 12-year-old male who sustained head trauma at 10 years 6 months of age was found to have Tanner grade 3 pubertal stage and advanced bone age. In addition, 3 prepubescent children also had advanced bone age with no other signs of precocious puberty and a normal GnRH test. For all children studied, the biochemical and hormonal laboratory measurements were in the normal range. Endocrine abnormalities were not found in children examined 4 months or more following sever...Continue Reading

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Citations

Sep 15, 2005·Journal of Neurotrauma·Manfred SchneiderGünter Karl Stalla
Aug 6, 2010·Journal of Neurotrauma·Rebecca Jane MoonJustin Huw Davies
Sep 21, 2016·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·David KrahulikJirina Zapletalova
May 1, 2002·Journal of Health Psychology·Gregory J BoyleEphrem Fernandez

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