Assessment of Esophageal High-Resolution Impedance Manometry in Patients with Nonobstructive Dysphagia

Gastroenterology Research and Practice
Zhaoyu LiuQin Yu

Abstract

High-resolution impedance manometry (HRIM) can calculate the bolus motion parameters and the ratio of complete esophageal transit besides the conventional esophageal dynamic parameters; therefore, we could better manage the patients with nonobstructive dysphagia (NOD) clinically. To analyze the HRIM parameter results of NOD patients and evaluate the characteristics of their esophageal motility and transit function. In total, 58 NOD patients were assessed and the clinical diagnoses were determined. HRIM was performed, and both conventional high-resolution manometry and esophageal transit parameters were analyzed. In 58 NOD patients, 28 patients had achalasia, 3 esophagogastric junction outflow obstruction, and 20 nonspecific esophageal motility disorders, and 7 were normal. Impedance results demonstrated that all the patients with achalasia exhibited incomplete esophageal transit (ICET), three patients with esophagogastric junction outflow obstruction showed ICET, and the average bolus transit time (BTT) was 6.6 ± 1.2 sec. In 20 nonspecific esophageal motility disorders, 13 patients with gastroenterologly reflux disease (GERD) presented ineffective esophageal motility and fragmented peristalsis, and 65.0% swallows had exhibited ...Continue Reading

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Methods Mentioned

BETA
ICET

Software Mentioned

ManoViewTM
SPSS
HRIM

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