PMID: 8943834Oct 1, 1996Paper

Assessment of exposure to polycyclic aromatic hydrocarbons in engine rooms by measurement of urinary 1-hydroxypyrene

Occupational and Environmental Medicine
B E MoenB E Hollund

Abstract

Machinists have an increased risk of lung cancer and bladder cancer, and this may be caused by exposure to carcinogenic compounds such as asbestos and polycyclic aromatic hydrocarbons (PAHs) in the engine room. The aim of this study was to investigate the exposure of engine room personnel to PAHs, with 1-hydroxypyrene in urine as a biomarker. Urine samples from engine room personnel (n = 51) on 10 ships arriving in different harbours were collected, as well as urine samples from a similar number of unexposed controls (n = 47) on the same ships. Urinary 1-hydroxypyrene was quantitatively measured by high performance liquid chromatography. The exposure to PAHs was estimated by a questionnaire answered by the engine room personnel. On two ships, air monitoring of PAHs in the engine room was performed at sea. Both personal monitoring and area monitoring were performed. The compounds were analysed by gas chromatography of two types (with a flame ionisation detector and with a mass spectrometer). Significantly more 1-hydroxypyrene was found in urine of personnel who had been working in the engine room for the past 24 hours, than in that of the unexposed seamen. The highest concentrations of 1-hydroxypyrene were found among engine roo...Continue Reading

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Citations

Feb 24, 2001·The Science of the Total Environment·F DorW Dab
Aug 30, 2008·Journal of Exposure Science & Environmental Epidemiology·Junfeng Jim ZhangWilliam Crain
May 16, 2007·Journal of Occupational and Environmental Hygiene·M D McCleanR F Herrick
Mar 16, 2011·The Annals of Occupational Hygiene·Yvette ChristopherJohn W Cherrie
May 21, 2011·The Annals of Occupational Hygiene·Michela AgostiniHans Kromhout
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Oct 20, 2005·Occupational and Environmental Medicine·L KaerlevP S Nielsen
Jul 28, 2010·Journal of Occupational Health·Marcus OldenburgClara Schlaich
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Oct 21, 2020·Scientific Reports·Ethan D EvansEric J Alm

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