PMID: 11320147Apr 26, 2001Paper

Assessment of genotoxic damage by the comet assay in white storks (Ciconia ciconia) after the Doñana Ecological Disaster

Mutagenesis
Nuria PastorF Cortés

Abstract

Single cell gel electrophoresis, the so-called "Comet" assay, was performed as a genotoxicity test in white storks sampled in an area heavily contaminated after the ecological disaster in south western Spain. This disaster occurred as a consequence of a massive toxic spillage of acid waste rich in heavy metals that impacted on the Doñana National Park. The importance of this protected area as a breeding and wintering site for many endangered bird species makes this analysis of DNA damage of special interest. Our results clearly show that white storks born in the contaminated area 1 year after the toxic spill bear a high burden of genetic damage as compared with control individuals. The possible implications for future survival as well as reproductive rate are discussed.

Citations

Apr 23, 2008·Cell Biology and Toxicology·Alok DhawanDevendra Parmar
Jul 1, 2002·Environmental Toxicology and Pharmacology·Jos C S Kleinjans, Frederik-Jan van Schooten
Jul 17, 2012·Journal of Agricultural and Food Chemistry·Estefanía Burgos-MorónMiguel López-Lázaro
May 4, 2013·Journal of Agricultural and Food Chemistry·José Manuel Calderón-MontañoMiguel López-Lázaro
Dec 31, 2002·Environmental Toxicology and Chemistry·Antonio Romero-RuizJuan López-Barea
Feb 15, 2013·Pharmacological Reports : PR·José M Calderón-MontañoMiguel López-Lázaro
Nov 28, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Andrea Bonisoli-AlquatiMichael D Wyatt
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Jan 17, 2009·Mutation Research·Jette RankKlara Jensen
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Oct 24, 2007·Environmental Pollution·Santiago MateosFelipe Cortés
Nov 12, 2016·Ecotoxicology and Environmental Safety·Cátia S A SantosSusana Loureiro
Oct 31, 2018·Drug Development Research·Estefanía Burgos-MorónJosé Manuel Calderón-Montaño
Dec 7, 2019·Toxicology Mechanisms and Methods·Elva I Cortés-GutiérrezJaime Gosálvez
Dec 18, 2019·Environmental Science and Pollution Research International·Shabana NazRifat Ullah Khan

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