Assessment of hematological, biochemical effects and genotoxicity among pesticide sprayers in grape garden

Journal of Occupational Medicine and Toxicology
Avinash Shivaji GaikwadRavichandran Beerappa

Abstract

Many studies revealed toxic effects of pesticides on pesticide handlers but very fewer studies have been reported among grape garden pesticide sprayers in India. The purpose of this study was to evaluate the effect of pesticides among grape garden sprayers. 27 pesticide sprayers in study group and 27 non sprayers in control group were recruited. Blood samples were analyzed for hematological profile, biochemical parameters and urine samples for oxidative stress, buccal mucosal cells for genotoxicity. For statistical analysis student's t-test and Mann Whitney U test were used. White blood cell (WBC) count was significantly decreased; uric acid and Malondialdehyde (MDA) level was significantly increased among study group. In present study the Micronucleus (MN) assay for buccal mucosal cell showed significant number of micronucleated cells in study group. These results suggest that pesticide sprayers in grape garden are under risk which need to be monitored continuously in large population and further study is warranted to correlate the pesticide exposure by assessing acetylcholinesterase activity, pesticide residue analysis and their personal habits.

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Citations

May 17, 2017·Environmental Science and Pollution Research International·Tatiana Vieira Souza ChavesMaria Elisabete Amaral de Moraes
Oct 25, 2016·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Rekhadevi Perumalla VenkataParamjit Grover
Apr 5, 2017·Environmental Science and Pollution Research International·Nagah M HassaninRanya A Amer
Mar 29, 2018·Drug and Chemical Toxicology·Aref SalehzadehTahereh Rezaii
Oct 17, 2018·The International Journal of Occupational and Environmental Medicine·Hamed JalilianShekoufeh Taheri
Aug 21, 2020·Environmental and Molecular Mutagenesis·Avinash S GaikwadDhananjayan Venugopal
Jun 28, 2019·Environmental Science and Pollution Research International·Paulina Arévalo-JaramilloNatalia Bailon-Moscoso
May 12, 2016·World Journal of Hepatology·Venerando RapisardaGaetano Bertino
Dec 22, 2016·Molecular Medicine Reports·Caterina LeddaVenerando Rapisarda
Jan 18, 2018·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Joice LermenPatrícia G Ardenghi
Mar 25, 2017·Molecular Medicine Reports·Venerando RapisardaCarla Loreto
Mar 17, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·David Lozano-PaniaguaAntonio F Hernández
Jun 5, 2021·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Aline de Souza Espindola SantosArmando Meyer

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Methods Mentioned

BETA
MDA
scraping

Software Mentioned

statistical package for social science ( SPSS )

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