Assessment of left ventricular function in patients with isolated severe disease of the left anterior descending artery: clinical, electrocardiographic, hemodynamic, and angiographic correlations
Catheterization and Cardiovascular Diagnosis
A S IskandrianC E Bemis
The purpose of this study was to define the spectrum of left ventriculographic (LV) abnormalities in 60 patients with isolated Greater Than or Equal To 90% diameter narrowing of the left anterior descending artery (LAD). The patients were divided into three groups: Group I (26 patients) had normal left ventricular (LV) function with ejection fraction (EF) of Greater Than 60% and no akinetic-dyskinetic segment representing abnormal contracting segments (ACS) of the left ventricular wall; Group II (15 patients) had mild to moderate LV dysfunction with EF of 40-60% and an akinetic-dyskinetic segment of Less Than 30% of the end diastolic perimeter (0-30%; mean, 11.6%) and Group III (19 patients) had severe LV dysfunction with EF Less Than 40%, or an akinetic-dyskinetic segment of Greater Than or Equal To 30% (30-81%; mean, 41.5%) or both. The data obtained from the history, physical examination, electrocardiogram (ECG), chest x-ray studies, hemodynamic studies, left ventriculography, and coronary arteriography were entered and filed on a memory disc in an IBM 370-168 computer. Analysis of the results showed: 1) more severe LV dysfunction is associated with increased incidence of large hearts, gallops, decreased cardiac output, and ...Continue Reading
Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.