Assessment of low-dose i.v. ketamine infusions for adjunctive analgesia

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Sarah KatorChristopher D Adams

Abstract

The results of a study evaluating all patients treated with adjunctive low-dose ketamine for analgesia over a three-year period are presented. A retrospective single-center analysis evaluated all adult patients who received adjunctive low-dose i.v. ketamine infusions from September 2010 to September 2013. Patients were excluded if they received concomitant oral ketamine, if ketamine was used to treat seizures, or if the patients received ketamine boluses without infusion. The primary endpoint was to identify the patient populations receiving low-dose intravenous ketamine. Secondary endpoints included an assessment of clinical variables and adverse events. Demographic information, level of care, clinical variables, adverse events, and patient outcomes were recorded. A total of 460 patients were evaluated. Of these, 396 were included in this analysis. Ketamine was administered to 69.9% of the patients in association with a surgical procedure, as opposed to 30.1% who received ketamine for medical management of pain. The percentage of patients receiving intensive care unit level care was 24%. Before initiation of ketamine, patient-reported pain scores averaged 7.1 ± 2.63 S.D.; during the ketamine infusion, patient-reported pain sco...Continue Reading

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Citations

May 10, 2017·The International Journal of Neuropsychopharmacology·Iku Tsutsui-KimuraKenji F Tanaka
Jun 9, 2020·Journal of Family Medicine and Primary Care·Abolfazl AbdollahpourBabak Hosseinzadeh Zoroufchi
Oct 2, 2020·Critical Care Nurse·Kyle Brown, Calvin Tucker
Apr 1, 2021·Pediatric Blood & Cancer·Emily M HarrisNatasha M Archer
Jan 11, 2021·Korean journal of anesthesiology·Abhijit Kumar, Amit Kohli
Jan 28, 2022·Journal of Palliative Medicine·Nicole ForthAnthony Grech

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