Assessment of lung inflammation with 18F-FDG PET during acute lung injury.

AJR. American Journal of Roentgenology
Nicolas de ProstMarcos F Vidal Melo

Abstract

The purpose of this review is to describe the current experimental and clinical data regarding the fundamentals and applications of (18)F-FDG PET during acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Lung inflammation is a key feature of ALI. During ALI, FDG PET can be used to monitor lung neutrophils, which are essential cells in the pathophysiologic mechanisms of ALI. Pulmonary FDG kinetics are altered during experimental and human ALI and are associated with regional lung dysfunction, histologic abnormalities, and prognosis. FDG PET may be a valuable noninvasive method for gaining comprehensive understanding of the mechanisms of ALI/ARDS and for evaluating therapeutic interventions.

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Citations

Aug 4, 2012·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Jose VenegasR Scott Harris
Dec 20, 2012·Journal of Thoracic Imaging·Thomas C KweeAbass Alavi
Jul 30, 2011·Journal of Applied Physiology·Nicolas de ProstMarcos F Vidal Melo
Aug 21, 2013·Critical Care : the Official Journal of the Critical Care Forum·Nicolas de ProstMarcos F Vidal Melo
Nov 19, 2013·Critical Care : the Official Journal of the Critical Care Forum·Davide ChiumelloSilvia Coppola
Mar 15, 2014·Radiation Oncology·Richard CastilloThomas Guerrero
Jul 4, 2012·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Dalia SahaMarcos F Vidal Melo
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Sep 8, 2012·Critical Care Research and Practice·Carmen Sílvia Valente BarbasCarlos Roberto Ribeiro Carvalho
Jan 12, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mehrdad PourfathiRahim R Rizi
May 23, 2018·American Journal of Respiratory and Critical Care Medicine·Gabriel C Motta-RibeiroMarcos F Vidal Melo
Jan 22, 2019·Anesthesiology·Maurizio CeredaRahim R Rizi
Mar 19, 2014·Critical Care Medicine·Nicolas de Prost, Marcos F Vidal Melo
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Jul 13, 2021·Infection and Immunity·Julian L GoggiLaurent Renia
Nov 10, 2021·The British Journal of Radiology·Avanti V Gulhane, Delphine L Chen

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