Assessment of lung perfusion impairment in patients with pulmonary artery-occlusive and chronic obstructive pulmonary diseases with noncontrast electrocardiogram-gated fast-spin-echo perfusion MR imaging

Journal of Magnetic Resonance Imaging : JMRI
Nobuhiko OgasawaraNaofumi Matsunaga

Abstract

To evaluate the ability of noncontrast electrocardiogram (ECG)-gated fast-spin-echo (FSE) perfusion MR images for defining regional lung perfusion impairment, as compared with technetium (Tc)-99m macroaggregated albumin (MAA) single-photon emission computed tomography (SPECT) images. After acquisition of ECG-gated multiphase FSE MR images during cardiac cycles at selected lung levels in nine healthy volunteers, 11 patients with pulmonary artery-occlusive diseases, and 15 patients with chronic obstructive pulmonary diseases (COPD), the subtracted perfusion-weighted (PW) MR images were obtained from the two-phase images of the minimum lung signal intensity (SI) during systole and the maximum SI during diastole, and were compared with SPECT images. ECG-gated PW images showed uniform but posture-dependent perfusion gradient in normal lungs and visualized the various sizes of perfusion defects in affected lungs. These defect sites were nearly consistent with those on SPECT images, with a significant correlation for the affected-to-unaffected perfusion contrast (r = 0.753; P < 0.0001). These MR images revealed that the pulmonary arterial blood flow in the affected areas of COPD was relatively preserved as compared with pulmonary arte...Continue Reading

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Citations

Apr 3, 2013·Journal of Thoracic Imaging·Sang Min LeeJi-Eun Kim
Mar 8, 2011·Academic Radiology·Yuka OkajimaHiroto Hatabu
Apr 15, 2009·Magnetic Resonance Imaging Clinics of North America·Elizabeth M Hecht, Andrew Rosenkrantz
Apr 17, 2013·Journal of Magnetic Resonance Imaging : JMRI·Christopher J FrançoisMark L Schiebler
Feb 3, 2021·The British Journal of Radiology·Yoshiharu OhnoHiroshi Toyama
May 7, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Yumi TanakaHiroshi Toyama
Dec 17, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Marcos F Vidal MeloJose G Venegas

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