Assessment of microcirculatory perfusion in healthy anesthetized cats undergoing ovariohysterectomy using sidestream dark field microscopy

Journal of Veterinary Emergency and Critical Care
Michelle E GoodnightAmy L Butler

Abstract

To: (1) determine the feasibility of using sidestream dark field microscopy (SDM) to measure microcirculatory parameters in healthy, anesthetized cats and (2) determine if surgical tissue manipulation and anesthesia time alter these parameters during ovariohysterectomy. Prospective observational study. University teaching hospital. Eighteen healthy female cats. Sublingual mucosa microcirculatory videos were obtained under general anesthesia preoperatively, intraoperatively, and postoperatively using an SDM device in healthy cats presenting for ovariohysterectomy. At each video acquisition point, macrovascular parameters (heart rate, blood pressure, pulse oximetry, end-tidal CO2) were recorded. Vascular analysis software was used to calculate standard microcirculatory parameters. Multivariate analysis was performed to compare microvascular and macrovascular parameters, as well as correlation with the effect of surgical manipulation and time under anesthesia. Twelve of 18 cats were included in final video analysis; 6 were removed for poor video quality. Values for total vessel density (TVD, 47.7 ± 8.39 mm/mm(2)), proportion of perfused vessels (PPV, 88.2 ± 5.95%), perfused vessel density (PVD, 43.0 ± 9.00 mm/mm(2)), microcirculat...Continue Reading

References

Jun 11, 1999·The American Journal of Physiology·H KergerM Intaglietta
Aug 10, 2000·The Veterinary Clinics of North America. Small Animal Practice·K E Torske, D H Dyson
Jul 5, 2001·Current Opinion in Critical Care·D De Backer, M J Dubois
Jan 17, 2002·The New England Journal of Medicine·E RiversUNKNOWN Early Goal-Directed Therapy Collaborative Group
Jan 23, 2003·Anesthesia and Analgesia·Zoë L S BrookesCharles S Reilly
Dec 24, 2003·American Heart Journal·Daniel De BackerJean-Louis Vincent
Dec 15, 2004·Chest·Lakhmir S ChawlaMuhammed Shah
May 6, 2006·NeuroImage·Patrick J BolanNoam Harel
Nov 11, 2006·Annals of Emergency Medicine·Stephen TrzeciakUNKNOWN Microcirculatory Alterations in Resuscitation and Shock Investigators
Dec 14, 2006·Critical Care : the Official Journal of the Critical Care Forum·Mehrnaz Hadian, Michael R Pinsky
Jun 26, 2007·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Fahad AttarN P Geary
Sep 12, 2007·Critical Care : the Official Journal of the Critical Care Forum·Daniel De BackerCan Ince
Jul 26, 2008·British Journal of Anaesthesia·M KochD Schmartz
Nov 15, 2008·Methods in Enzymology·Ian C MacDonald, Ann F Chambers
Jun 19, 2009·Critical Care : the Official Journal of the Critical Care Forum·Arnaldo DubinCan Ince
Jun 26, 2009·Intensive Care Medicine·Ryan C ArnoldSteven M Hollenberg
Nov 7, 2009·Critical Care Clinics·Brian CasserlyMitchell M Levy
Dec 19, 2009·Journal of Veterinary Emergency and Critical Care·Deborah C SilversteinKenneth J Drobatz
Feb 25, 2010·Current Opinion in Critical Care·Daniel De BackerDiamantino Salgado
Jul 29, 2010·Current Opinion in Critical Care·Namkje A R VellingaE Christiaan Boerma
Aug 7, 2010·Intensive Care Medicine·Daniel De BackerJean-Louis Vincent
Apr 2, 2011·American Journal of Veterinary Research·Ann M Peruski, Edward S Cooper

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Citations

Feb 19, 2020·Journal of Veterinary Emergency and Critical Care·Sarah GaudetteManuel Boller
Oct 28, 2020·American Journal of Veterinary Research·Kaitlyn M MullenJenny Groover

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