PMID: 11930185Apr 4, 2002Paper

Assessment of myocardial viability by positron emission tomography

Nuclear Medicine Communications
George Segall

Abstract

Accurate assessment of myocardial viability is critical for identifying patients likely to benefit from coronary revascularization. Positron emission tomography (PET) has several advantages over single photon emission computed tomography (SPECT), including higher sensitivity and specificity, as well as the ability to measure myocardial blood flow and myocardial metabolism in absolute terms, which is important in understanding the pathophysiology of ischemic cardiomyopathy. The most commonly used PET tracer is [18F]2-fluoro-2deoxy-D-glucose (FDG). The dependence of ischemic myocardium on glucose metabolism makes FDG an ideal tracer in this setting. Studies have shown positive and negative predictive values for the detection of viable myocardium in the range of 48-94%, and 73-96%, respectively. FDG is superior to SPECT using thallium or technetium myocardial perfusion agents, as well as echocardiography with dobutamine infusion. FDG PET also provides important prognostic information. Patients with evidence of myocardial viability by FDG PET have fewer cardiac events and survive longer if revascularized compared to patients who are treated medically. This article will review myocardial metabolism, PET procedures and interpretive c...Continue Reading

References

Jul 15, 1993·The American Journal of Cardiology·P Perrone-FilardiR O Bonow
Jan 1, 1997·Journal of the American College of Cardiology·S SawadaH Feigenbaum
Mar 1, 1997·Journal of the American College of Cardiology·R S BeanlandsE Fallen
Nov 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·C S DuvernoyM Schwaiger
Mar 21, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·N P SandM Rehling
Dec 30, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M F Di CarliJ Maddahi
Aug 26, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·E G DePueyH Salensky
Nov 21, 2001·Coronary Artery Disease·A Blum, R O Cannon

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Citations

Sep 17, 2005·Annals of Nuclear Medicine·Takashi ItohOsamu Inoue
Jul 4, 2012·International Journal of Computer Assisted Radiology and Surgery·Martina MarinelliDanilo Neglia
Jul 1, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rob S B Beanlands, George Youssef
Dec 12, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fergus I McKiddieMohaned Egred
Mar 20, 2008·Nuclear Medicine Communications·Arman Rahmim, Habib Zaidi
Jul 26, 2011·AJR. American Journal of Roentgenology·Daniel Y Lee, King C P Li
Apr 17, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Carolyn J AndersonHenry F VanBrocklin
Feb 16, 2010·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Cara L FerreiraChris Orvig
Aug 2, 2007·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Cara L FerreiraChris Orvig
Jun 25, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Angus Z LauCharles H Cunningham
Oct 22, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nishtha Sareen, Karthik Ananthasubramaniam
Nov 10, 2017·Current Treatment Options in Cardiovascular Medicine·Brian M Salata, Parmanand Singh
Jan 20, 2010·Technology in Cancer Research & Treatment·H F WehrlB J Pichler
Aug 15, 2006·Inorganic Chemistry·Cara L FerreiraChris Orvig

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