Assessment of neopterin level and severity in lichen planus patients treated with narrow-band ultraviolet B

Journal of Cosmetic Dermatology
Fathia M Khattab, Mai A Samir

Abstract

Neopterin is a cellular immunity biochemical marker. Serum and saliva neopterin levels have been reported to increase in lichen Planus. Nonetheless, analysis has not yet been made for the direct link between narrow band ultraviolet B and severity of Lichen planus. We aimed to assess serum neopterin levels in patients who receive narrow band ultraviolet B therapy treatment with lichen planus, paired with the severity of the disease. The study consisted of 35 lichen planus patients and 30 healthy individuals. A 35 patient group received narrow band ultraviolet B therapy. An enzyme-related immunosorbent assay procedure was used in serum neopterin analysis before and post-therapy. The correlation between the level and severity of the patient group was statistically significant (P = .001). In patients with severe disease, serum neopterin levels were significantly increased. Also, in the severe lichen planus group, the serum neopterin level was statistically higher than that of the mild or moderate groups (P = .001).Also, a significant decrease was seen following therapy according to serum neopterin level. Serum neopterin levels are a useful marker for the assessment of the severity and effectiveness of narrow band ultraviolet therap...Continue Reading

References

Nov 1, 1992·The British Journal of Dermatology·C C HarlandC A Holden
Jun 3, 1999·The British Journal of Dermatology·M S DuthieM Norval
Aug 23, 2000·Acta Dermato-venereologica·M Sánchez-RegañaP Umbert
May 11, 2002·Current Drug Metabolism·C MurrD Fuchs
Jul 9, 2002·International Journal of Dermatology·Atul Taneja, Charles R Taylor
Oct 11, 2003·Photodermatology, Photoimmunology & Photomedicine·Hayriye SaricaoğluSükran Tunali
Mar 5, 2005·Annales de dermatologie et de vénéréologie·F HabibL Meunier
Mar 21, 2008·Photodermatology, Photoimmunology & Photomedicine·Felix PavlotskyHenri Trau
Sep 6, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·H GamilF Ahmed
Nov 22, 2008·Journal of the American Academy of Dermatology·Shanu Kohli Kurd, Joel M Gelfand
Dec 22, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Peter MayersbachHarald Schennach
Jan 25, 2012·Dermatology : International Journal for Clinical and Investigative Dermatology·E VerhaegheJ Lambert
Apr 25, 2012·Journal of Oral and Maxillofacial Pathology : JOMFP·N LavanyaK Ranganathan
Jun 18, 2014·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ayman Abdel-HaqMaria Chomyszyn-Gajewska
Sep 5, 2015·Cutaneous and Ocular Toxicology·Berna SolakTeoman Erdem

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