Assessment of neurological manifestations in hospitalized patients with COVID-19

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
Marco LuigettiGEMELLI AGAINST COVID-19 group

Abstract

The objective of this study was to assess the neurological manifestations in a series of consecutive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients, comparing their frequency with a population hospitalized in the same period for flu/respiratory symptoms, finally not related to SARS-CoV-2. Patients with flu/respiratory symptoms admitted to Fondazione Policlinico Gemelli hospital from 14 March 2020 to 20 April 2020 were retrospectively enrolled. The frequency of neurological manifestations of patients with SARS-CoV-2 infection was compared with a control group. In all, 213 patients were found to be positive for SARS-CoV-2, after reverse transcriptase polymerase chain reaction on nasal or throat swabs, whilst 218 patients were found to be negative and were used as a control group. Regarding central nervous system manifestations, in SARS-CoV-2-positive patients a higher frequency of headache, hyposmia and encephalopathy always related to systemic conditions (fever or hypoxia) was observed. Furthermore, muscular involvement was more frequent in SARS-CoV-2 infection. Patients with COVID-19 commonly have neurological manifestations but only hyposmia and muscle involvement seem more frequent compared wit...Continue Reading

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Citations

Nov 17, 2020·Journal of the American Geriatrics Society·Marcello CovinoUNKNOWN GEMELLI AGAINST COVID-19 Group
Jan 12, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marina RomozziMarco Luigetti
Jan 6, 2021·Journal of Psychosomatic Research·Michael HawkinsKathleen Ann Sheehan
Nov 11, 2020·Journal of Clinical Medicine·Marco Luigetti, Giovanni Frisullo
Apr 9, 2021·PloS One·Fernando Daniel Flores-SilvaErwin Chiquete
May 8, 2021·Orphanet Journal of Rare Diseases·Thomas H BrannaganFrederick L Ruberg
May 14, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Isabel SiowAdeline Ng
Jul 15, 2021·ACS Chemical Neuroscience·Vitalakumar DS J S Flora
Aug 25, 2021·Journal of Translational Medicine·Yuanyuan HeHong Zhang
Aug 27, 2021·The International Journal of Neuroscience·Zeina Hassan OusseiranWafaa Takash Chamoun

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