PMID: 12784578Jun 6, 2003Paper

Assessment of nonpenetrating deep sclerectomy with reticulated hyaluronic acid implant SKGEL and/or preoperative application of 5-luorouracil: results of 2 and a half years

Bulletin de la Société belge d'ophtalmologie
M Detry-Morel, S De Temmerman

Abstract

To assess the effectiveness and the safety of deep sclerectomy (DS) with reticulated hyaluronic acid implant (SKGEL) and/or 5-Fluorouracile (5-FU). 42 phakic eyes (42 patients) (mean age: 61.0 +/- 11.5 years) with medically uncontrolled open angle glaucoma and without history of previous filtering procedure were included in this non-randomized retrospective study. According to the peroperative protocol, the patients were categorized into 3 groups: DS + SKGEL (7 eyes), DS + 5-FU (50/mg/ml during 3 minutes) (13 eyes) and group C with SKGEL and 5-FU simultaneously (22 eyes). The mean follow up was 30.6 +/- 9.2 months and was significantly shorter in group C. The 3 groups were comparable with respect to the age of the patients, the severity of glaucomatous defects, the distribution of the target IOP, the mean number and duration of preoperative medications as well as to the mean preoperative visual acuity and IOP. The mean IOP was significantly decreased from 27.3 +/- 3.2 mm Hg to 16.1 +/- 3.7 3.7 mm Hg (p < 0.0001) and was not significantly different between the 3 groups at 24 months follow up (p > 0.05). Mean visual acuity was not significantly altered in the 3 groups (p > 0.05). Complete (target IOP reached without medication or...Continue Reading

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