Assessment of occupational cytogenetic risk, among petrol station workers

Bulletin of Environmental Contamination and Toxicology
Sadhanandhan BindhyaK Sasikala

Abstract

The focal aim of this study was to assess the frequency of chromosomal aberrations (CA) including chromatid type aberrations (CTA) and chromosomal type aberrations (CSA), micronucleus (MN) and XRCC1 399 Arg/Gln polymorphism in the peripheral blood lymphocytes of 27 petrol pump workers and same number of controls to explore the possible cytogenetic risk on occupational exposure to petrol vapors. The exposed subjects and controls were classified into two groups based on their age (group I < 40 years; group II > 40 years) apart from the classification of the exposed subjects based on their exposure duration (> 8 and < 8 years). CTA and MN frequency were significantly higher in petrol pump workers (p < 0.05) with longer work duration. CTA was found to increase with age in the exposed subjects as well as controls, with exposed subjects showing a statistically higher degree. This effect was not observed in MN. A significantly higher frequency of MN was observed in the smoking petrol pump workers than in control smokers (p < 0.05). No association was found between smoking and CA in both subjects. The study on XRCC1 399 Arg/gln polymorphism in petrol pump workers demonstrated very less difference in allele frequency compared to control...Continue Reading

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Jul 16, 2008·Bulletin of Environmental Contamination and Toxicology·V BalachandarK Sasikala

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Citations

Dec 3, 2013·Environmental Monitoring and Assessment·Patrícia TrevisanPaulo Ricardo Gazzola Zen
Feb 13, 2016·International Archives of Occupational and Environmental Health·R N NaidooA Phulukdaree
Apr 12, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jasminka MrdjanovićVladimir Jurišić
May 10, 2016·Environmental Monitoring and Assessment·Rozana Oliveira GonçalvesMarco Antônio Vasconcelos Rêgo
Nov 12, 2019·International Journal of Environmental Health Research·Pauline McLooneDinara Kenessary
Jul 28, 2021·Journal of Environmental Management·Anirban Goutam MukherjeeAbilash Valsala Gopalakrishnan

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