PMID: 3756114Sep 1, 1986Paper

Assessment of occupational exposure to 4,4'-diaminodiphenylmethane (methylene dianiline) by gas chromatography-mass spectrometry analysis of urine

British Journal of Industrial Medicine
J CockerH K Wilson

Abstract

A new specific and sensitive method has been used to monitor workers from five different factories where 4,4'-diaminodiphenylmethane (methylene dianiline) (DDM) was being used. The isolation and identification of an N-acetyl conjugate of DDM, a major metabolite of DDM found in human urine, is reported for the first time. The use of this biological monitoring method will allow the assessment of the absorption of DDM and help in monitoring improvements in work practices, particularly where exposure may occur through pathways other than inhalation.

References

Oct 1, 1978·Toxicology·W B DeichmannE Blum
Jan 1, 1985·International Archives of Occupational and Environmental Health·A HesbertJ De Ceaurriz
Jan 1, 1985·International Archives of Occupational and Environmental Health·P DucosR Gaudin
May 1, 1970·Die Naturwissenschaften·D Steinhoff, E Grundmann
Aug 8, 1974·The New England Journal of Medicine·D B McGill, J D Motto
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Apr 1, 1983·Journal of Pharmacokinetics and Biopharmaceutics·M S LennardH F Woods

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Citations

Jan 1, 1995·International Archives of Occupational and Environmental Health·M DaleneP Brunmark
Mar 1, 1993·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S A HotchkissJ Caldwell
Aug 1, 1994·Occupational and Environmental Medicine·J CockerH K Wilson
Aug 12, 2008·Toxicology and Applied Pharmacology·Kan ChenTammy R Dugas
May 30, 2003·Toxicological Sciences : an Official Journal of the Society of Toxicology·Mary F KanzVicente Santa Cruz
May 17, 2000·Journal of Biomedical Materials Research·H M Do Luu, J C Hutter
Dec 25, 2019·Analytical and Bioanalytical Chemistry·Maggy LépineSébastien Gagné
Sep 22, 2017·Chemical Research in Toxicology·Gabriele Sabbioni

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