Assessment of outcomes and differences between in- and out-of-hospital cardiac arrest patients treated with cardiopulmonary resuscitation using extracorporeal life support

Resuscitation
Eisuke KagawaNozomu Oda

Abstract

Cardiopulmonary resuscitation (CPR) using extracorporeal life support (ECLS) for in-hospital cardiac arrest (IHCA) patients has been assigned a low-grade recommendation in current resuscitation guidelines. This study compared the outcomes of IHCA and out-of-hospital cardiac arrest (OHCA) patients treated with ECLS. A total of 77 patients were treated with ECLS. Baselines characteristics and outcomes were compared for 38 IHCA and 39 OCHA patients. The time interval between collapse and starting ECLS was significantly shorter after IHCA than after OHCA (25 (21-43)min versus 59 (45-65)min, p<0.001). The weaning rate from ECLS (61% versus 36%, p=0.03) and 30-day survival (34% versus 13%, p=0.03) were higher for IHCA compared with OHCA patients. IHCA patients had a higher rate of favourable neurological outcome compared to OHCA patients, but the difference was not statistically significant (26% versus 10%, p=0.07). Kaplan-Meier analysis showed improved 30-day and 1-year survival for IHCA patients treated with ECLS compared to OHCA patients who had ECLS. However, multivariate stepwise Cox regression model analysis indicated no difference in 30-day (odds ratio 0.94 (95% confidence interval 0.68-1.27), p=0.67) and 1-year survival (0.99...Continue Reading

References

Feb 22, 2002·The New England Journal of Medicine·UNKNOWN Hypothermia after Cardiac Arrest Study Group
Jan 22, 2003·Journal of the American College of Cardiology·Yih-Sharng ChenShoei-Shan Wang
Nov 15, 2006·The New England Journal of Medicine·Elizabeth H BradleyHarlan M Krumholz
Jul 16, 2008·Resuscitation·Satoshi KurisuHiroki Ikenaga

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Citations

Aug 31, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Bulent GorenekIrene Savelieva
May 3, 2014·Current Opinion in Critical Care·David FagnoulDaniel De Backer
Apr 15, 2014·Mayo Clinic Proceedings·Keith M SwetzWilliam L Lanier
May 10, 2013·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Jürgen LeickHelge Möllmann
Dec 3, 2014·Emergency Medicine Clinics of North America·John C Greenwood, Daniel L Herr
Dec 20, 2012·Critical Care : the Official Journal of the Critical Care Forum·Scott A GoldbergPaul E Pepe
Aug 18, 2010·Critical Care : the Official Journal of the Critical Care Forum·Eisuke KagawaNozomu Oda
Nov 14, 2013·European Heart Journal. Acute Cardiovascular Care·Chiara LazzeriSerafina Valente
Oct 1, 2013·Current Opinion in Cardiology·Eisuke KagawaYasuki Kihara
Jul 26, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Loic BelleDominique Blin
Aug 26, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christian JungHans Reiner Figulla
Feb 11, 2016·Herzschrittmachertherapie & Elektrophysiologie·Markus Wolfgang Ferrari
Nov 26, 2013·Annals of Emergency Medicine·Stephen P WallUNKNOWN NYC uDCDD Study Group
Oct 22, 2015·Critical Care Medicine·Elena SpinelliRobert W Neumar
Aug 30, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Bulent GorenekUwe Zeymer
Sep 20, 2015·International Emergency Nursing·Edward Baker, Geraldine Lee
Jan 13, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Jennifer M BanayanGianluca Torregrossa
Dec 20, 2015·Artificial Organs·Natacha RousseAndre Vincentelli
Dec 17, 2015·Best Practice & Research. Clinical Anaesthesiology·Nicolò PatronitiLeonello Avalli
Sep 15, 2015·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jennifer BrunetCedric Daubin
Mar 21, 2016·The Journal of Thoracic and Cardiovascular Surgery·Amedeo Anselmi, Erwan Flécher
Jul 21, 2015·The Journal of Thoracic and Cardiovascular Surgery·Amedeo AnselmiVito Giovanni Ruggieri
Apr 12, 2014·BioMed Research International·Tomas HenlinMilos Dobias
Aug 21, 2013·Resuscitation·Thomas Müller, Matthias Lubnow

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