Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications.

JAMA Otolaryngology-- Head & Neck Surgery
Edward D McCoul

Abstract

Sinonasal remedies are the most frequently purchased category of over-the-counter (OTC) drugs in the United States. A variety of options for relief are available under proprietary names, although the actual number of available options may not be readily appreciated by the consumer or the clinician. To determine the prevalence of specific ingredients in OTC sinonasal products. This cross-sectional study took physical inventory of brand-name and generic OTC drugs marketed as sinus, cold, allergy, or nasal remedies. Retail pharmacies in New Orleans, Louisiana, commercial websites, and the Drugs, Herbs and Supplements section of MedlinePlus and drugs.com were searched. Data were collected and analyzed from July 1 to 31, 2018. Frequency of active ingredients in OTC formulations. Five pharmacies were visited to identify 18 brands, for which the commercial websites were then searched. The 14 most common brands represented 211 unique products. Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the same active ingredient. Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlorpheniramine maleate, bro...Continue Reading

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May 31, 2019·JAMA Otolaryngology-- Head & Neck Surgery·Edward D McCoulAmit S Patel

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