Assessment of rectocolonic morphology and function in patients with Chagas disease in Barcelona (Spain)

The American Journal of Tropical Medicine and Hygiene
Fernando SalvadorIsrael Molina

Abstract

The aim of this study was to determine the relationship between colonic symptoms, radiological abnormalities, and anorectal dysfunction in patients with Chagas disease. We performed a cross-sectional study of untreated patients diagnosed with Chagas disease. All patients were evaluated clinically (by a questionnaire for colonic symptoms based on Rome III criteria) and underwent a barium enema and anorectal manometry. A control group of patients with functional constipation and without Chagas disease was included in the study. Overall, 69 patients were included in the study: 42 patients were asymptomatic and 27 patients had abdominal symptoms according to Rome III criteria. Anorectal manometry showed a higher proportion of abnormalities in symptomatic patients than in asymptomatic ones (73% versus 21%, respectively; P < 0.0001). Megarectum was detected in a similar proportion in the different subgroups regardless of the presence of symptoms or abnormalities in anorectal functions. Among non-Chagas disease patients with functional constipation, 90% had an abnormal anorectal manometry study. Patients with Chagas disease present a high proportion of constipation with dyssynergic defecation in anorectal manometry but a low prevalenc...Continue Reading

References

Dec 13, 2006·Memórias do Instituto Oswaldo Cruz·María Del Carmen Sánchez-GuillénRicardo Pérez-Fuentes
Feb 28, 2007·The American Journal of Surgical Pathology·Guido IantornoVincenzo Villanacci
Mar 27, 2007·Digestive Diseases and Sciences·A B M da SilveiraJ B Furness
Jul 16, 2008·Arquivos De Gastroenterologia·Simone CavenaghiJoão Gomes Netinho
Nov 26, 2009·Acta Tropica·Gabriel A Schmunis, Zaida E Yadon
Jul 31, 2010·The Lancet Infectious Diseases·François-Xavier LescureGilles Pialoux
Nov 16, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A Pérez-AyalaR López-Vélez
Feb 8, 2011·Annals of Tropical Medicine and Parasitology·A Pérez-AyalaR López-Vélez
Mar 10, 2012·The American Journal of Tropical Medicine and Hygiene·Cristina RieraMontserrat Portús
Dec 18, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F SalvadorI Molina

❮ Previous
Next ❯

Citations

Nov 23, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Jordi SerraUNKNOWN Functional Constipation Guidelines Working Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

AJR. American Journal of Roentgenology
C D JohnsonH C Carlson
International Journal of Colorectal Disease
F PuccianiC Cortesini
Acta Tropica
Alfonso J Rodriguez-MoralesDalmiro J Cazorla-Perfetti
© 2021 Meta ULC. All rights reserved