PMID: 8598235Mar 1, 1996Paper

Assessment of spleen size using gamma camera scintigraphy in newly diagnosed patients with essential thrombocythaemia and polycythaemia vera

European Journal of Haematology
J CarneskogJack Kutti

Abstract

By using gamma camera imaging the spleen size was assessed in 18 consecutive patients with essential thrombocythaemia (ET) and in 18 consecutive patients with polycythaemia vera (PV). All ET and PV patients were newly diagnosed and had not received any myelosuppressive therapy prior to study. The spleen areas in both posterior and left lateral projections were determined. Eighteen consecutive patients with idiopathic thrombocytopenic purpura (ITP) served as a control group since by definition they do not present with splenic enlargement; in these latter subjects the mean posterior and left lateral splenic areas were almost identical (48 +/- 15 and 47 +/- 17 cm2, respectively). In comparison with this control group patients with ET and PC had significantly larger spleens. In both ET and in PV patients the left lateral spleen scan area exceeded the posterior one. Patients with PV had larger splenic areas in both projections than did patients with ET, but the differences were not statistically significant. Compared to the ITP patients it was found that at least 50% of the ET patients and at least 61% of the PV patients at diagnosis presented with splenomegaly.

References

Jun 1, 1991·British Journal of Haematology·T C Pearson
Feb 1, 1990·European Journal of Haematology·J Kutti
Sep 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B RidellL Enerbäck
Mar 1, 1989·British Journal of Haematology·J M DudleyT C Pearson
Apr 1, 1988·European Journal of Haematology·M MessinezyT C Pearson
Feb 1, 1986·British Journal of Haematology·J E Van de PetteG Wetherley-Mein
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Aug 1, 1993·Annals of Hematology·P J van Genderen, J J Michiels
Sep 1, 1993·European Journal of Haematology·P ReveszJ Kutti

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Citations

Jan 26, 1999·European Journal of Haematology·J CarneskogJ Kutti
Oct 6, 1997·European Journal of Haematology·B AndréassonJ Kutti
Jan 16, 2014·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Sunny Joseph VargheseRamesh Kumar
Mar 12, 2021·International Journal of Hematology·Myung-Won LeeDeog-Yeon Jo
Jan 20, 2000·Baillière's Clinical Haematology·T C Pearson

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