Assessment of structural cardiac abnormalities and diastolic function in women with gestational diabetes mellitus

Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease
Alexandra P OliveiraVera T M Borges

Abstract

The main manifestation of hyperglycaemia during pregnancy is gestational diabetes mellitus. It can herald diabetes mellitus type 2 and its deleterious long-term effects, such as hypertension and cardiovascular disease. The aim of this study was to assess diastolic function in women with gestational diabetes mellitus, one of the first signs of future cardiovascular disease. A total of 21 women with gestational diabetes mellitus and 23 healthy pregnant women (control group) between 34 and 37 weeks of gestation underwent echocardiographic assessment. The diagnosis of gestational diabetes mellitus was made in agreement with the American Diabetes Association criteria. Echocardiographic images obtained were analysed according to the criteria of the American Society of Echocardiography. Data were analysed using Pearson correlation coefficient, analysis of variance and Student's t-test. Women with gestational diabetes mellitus had higher posterior wall and interventricular septum thickness, increased left ventricular mass and left ventricular mass index, lower early diastolic annular velocity and early diastolic annular velocity/late diastolic annular velocity ratio. There was a positive correlation between left ventricular mass index ...Continue Reading

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Citations

Sep 30, 2016·Journal of Clinical Ultrasound : JCU·Srinidhi J MeeraCynthia C Taub
Dec 1, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B S BuddebergB Thilaganathan
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Sep 14, 2019·Canadian Journal of Physiology and Pharmacology·Yun LiuFutian Tang
Apr 27, 2020·American Journal of Obstetrics and Gynecology·Jesica AguileraMarietta Charakida
Mar 11, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Yujing He, Na Wu
May 6, 2021·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A M Company CalabuigC De Paco Matallana

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